公开(公告)号：US20240246994A1

公开(公告)日：2024-07-25

申请号：US18559682

申请日：2022-05-12

Applicant: Betta Pharmaceuticals Co., Ltd.

Inventor： Houxian ZU ,  Liang CHEN ,  Xizhen SONG ,  Xintao ZHAO ,  Kai CHEN ,  Xiaoyun LIU ,  Jin WANG ,  Zhifang XIA ,  Ying XU ,  Yuanzheng ZHOU ,  Lieming DING ,  Jiabing WANG

IPC: C07D498/04 ,  A61K31/553 ,  A61P35/00

CPC classification number: C07D498/04 ,  A61K31/553 ,  A61P35/00

Abstract: Disclosed are a polymorph of (S)-1-(2-((S)-3-cyclopropyl-5-isopropyl-2,4-dioxoimidazolidin-1-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)pyrrolidine-2-carboxamide, a composition comprising the polymorph, a use method therefor and a preparation method therefor.

公开(公告)号：US20230053342A1

公开(公告)日：2023-02-23

申请号：US17773771

申请日：2020-11-04

Applicant: BETTA PHARMACEUTICALS CO., LTD

Inventor： Houxian ZU ,  Xizhen SONG ,  Kai CHEN ,  Xiangyong LIU ,  Jie CHEN ,  Yajing BIAN ,  Lieming DING ,  Jiabing WANG

IPC: C07D498/04 ,  C07D513/04 ,  A61P35/00

Abstract: An imidazolidinone compound represented by formula (I), or a stereoisomer thereof, a geometric isomer thereof, or a tautomer thereof, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing the compound, a synthesis method therefor and use thereof.