公开(公告)号：US20230390270A1

公开(公告)日：2023-12-07

申请号：US18021643

申请日：2021-08-19

Applicant: BIOGEN MA INC.

Inventor： Shibeshih Belachew ,  Ellen Cahir-McFarland ,  Zhaohui Shao ,  Hui-Hsin Tsai ,  Ru Wei

IPC: A61K31/445 ,  A61K45/06 ,  A61P9/10

CPC classification number: A61K31/445 ,  A61P9/10 ,  A61K45/06

Abstract: Disclosed is a method of treating a human subject with multiple sclerosis. The method comprises administering to the subject in the absence of a cholesterol lowering drug an effective amount of Compound 1: or a pharmaceutically acceptable salt thereof.

公开(公告)号：US20230310405A1

公开(公告)日：2023-10-05

申请号：US18021654

申请日：2021-08-19

Applicant: BIOGEN MA INC.

Inventor： Shibeshih Belachew ,  Ellen Cahir-McFarland ,  Zhaohui Shao ,  Hui-Hsin Tsai ,  Ru Wei

IPC: A61K31/445 ,  A61K45/06 ,  A61P3/06

CPC classification number: A61K31/445 ,  A61K45/06 ,  A61P3/06

Abstract: Disclosed is a method of lowering elevated cholesterol plasma levels in a subject. Also disclosed is a method of treating hypercholesterolemia in a subject. The methods comprise administering to the subject in the absence of a cholesterol lowering drug an effective amount of Compound 1 or pharmaceutically acceptable salt thereof.