公开(公告)号：US20190049445A1

公开(公告)日：2019-02-14

申请号：US15569005

申请日：2016-04-21

Applicant: BIOMERIEUX

Inventor： Maud ARSAC ,  Pierre-Jean COTTE-PATTAT ,  Victoria GIRARD ,  Valérie MONNIN

IPC: G01N33/569 ,  H01J49/00 ,  C12Q1/04

Abstract: A method for identifying by mass spectrometry an unknown microorganism subgroup among a set of reference subgroups, including a step of constructing one knowledgebase and one classifying model per associated subgroup on the basis of the acquisition of at least one set of learning spectra of microorganisms identified as belonging to the subgroups of a group and including: constructing an adjusting model allowing mass-to-charge offsets of the acquired spectra to be corrected on the basis of reference masses-to-charges that are common to the various subgroups; adjusting the masses-to-charges of all of the lists of peaks of the learning spectra and constructing one classifying model per subgroup and the associated knowledgebase on the basis of the adjusted learning spectra.

公开(公告)号：US20130172209A1

公开(公告)日：2013-07-04

申请号：US13739447

申请日：2013-01-11

Applicant: BIOMERIEUX

Inventor： Maud ARSAC ,  Bertrand BONNAUD ,  Francois MALLET ,  Jean-Philippe PICHON

IPC: C12Q1/70

CPC classification number: C12Q1/702 ,  C12Q1/6886 ,  C12Q2600/154 ,  C12Q2600/158

Abstract: The invention relates to a method for in vitro diagnosis or prognosis of testicular cancer which comprises a step of detecting the presence or absence of at least one expression product from at least one nucleic acid sequence selected from the sequences identified in SEQ ID NOS: 1 to 6 or from the sequences which exhibit at least 99% identity with one of the sequences identified in SEQ ID NOS: 1 to 6, to isolated nucleic acid sequences and to the use thereof as a testicular cancer marker.

Abstract translation: 本发明涉及一种用于体外诊断或睾丸癌预后的方法，其包括从至少一种选自SEQ ID NO：1中鉴定的序列的核酸序列检测至少一种表达产物的存在或不存在的步骤， 6或来自与SEQ ID NO：1至6中鉴定的一个序列具有至少99％同一性的序列，或与分离的核酸序列及其作为睾丸癌标志物的用途的序列。