专利检索 ap:("BIOMUNEX PHARMACEUTICALS") AND inv:"RICHARD J. MORSE" 第 1 页

1.

发明申请
STABLE MULTISPECIFIC ANTIBODIES 审中-公开

公开(公告)号：US20200299413A1

公开(公告)日：2020-09-24

申请号：US16498421

申请日：2018-03-27

申请人： BIOMUNEX PHARMACEUTICALS

发明人： EUGENE ZHUKOVSKY , OLIVIER LEGER , RICHARD J. MORSE

IPC分类号： C07K16/46 , C07K16/28 , C12N15/63

摘要： The invention relates to multispecific antibody constructs comprising Fab fragments having a particular set of mutations at the interface of the CH1 and CL domains, said mutations preventing heavy chain/light chain mispairing.

2.

发明公开
BINDING MOLECULES TO CD38 AND PD-L1 审中-公开

公开(公告)号：US20230146591A1

公开(公告)日：2023-05-11

申请号：US18056279

申请日：2022-11-17

申请人： BIOMUNEX PHARMACEUTICALS

发明人： EUGENE ZHUKOVSKY , OLIVIER LEGER , RICHARD J. MORSE

IPC分类号： C07K16/28

CPC分类号： C07K16/2896 , C07K16/2827 , C07K2317/31 , C07K2317/732 , C07K2317/734 , C07K2317/92

摘要： The present invention relates to a bispecific molecule comprising at least one anti-CD38 domain and at least one anti-PD-L1 domain, which are capable of simultaneous binding to CD38 and PD-L1 antigens, respectively.

3.

发明申请
BINDING MOLECULES TO CD38 AND PD-L1 审中-公开

公开(公告)号：US20200010559A1

公开(公告)日：2020-01-09

申请号：US16088181

申请日：2017-03-27

申请人： BIOMUNEX PHARMACEUTICALS

发明人： EUGENE ZHUKOVSKY , OLIVIER LEGER , RICHARD J. MORSE

IPC分类号： C07K16/28

摘要： The present invention relates to a bispecific molecule comprising at least one anti-CD38 domain and at leak one anti-PD-L1 domain, which are capable of simultaneous binding to CD38 and PD-L1 antigens, respectively.