专利检索 ap:("BIOMUNEX PHARMACEUTICALS" OR "INSTITUT CURIE" OR "INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)") AND inv:"MUSTAPHA FAROUDI" 第 1 页

1.

发明公开
MULTISPECIFIC ANTIBODIES THAT BIND BOTH MAIT AND TUMOR CELLS 审中-公开

公开(公告)号：US20230322952A1

公开(公告)日：2023-10-12

申请号：US17791549

申请日：2021-01-08

申请人： BIOMUNEX PHARMACEUTICALS , INSTITUT CURIE , INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

发明人： OLIVIER LANTZ , SEBASTIAN AMIGORENA , MICHAEL SAITAKIS , MAUDE GUILLOT-DELOST , EUGENE ZHUKOVSKY , PIERRE-EMMANUEL GERARD , MUSTAPHA FAROUDI

IPC分类号： C07K16/46 , A61P35/00

CPC分类号： C07K16/468 , A61P35/00 , C07K2317/31 , C07K2317/55 , C07K2317/522 , C07K2317/565

摘要： The invention provides a multispecific molecule capable of simultaneous binding to a Mucosal Associated Invariant T (MAIT) cell and a tumor cell, which multispecific molecule comprises at least one domain that specifically binds a Vα7.2 T cell receptor (TCR) and at least one domain that specifically binds a tumor associated antigen (TAA).