公开(公告)号：US20210032628A1

公开(公告)日：2021-02-04

申请号：US16963998

申请日：2019-01-29

申请人： BIONEER CORPORATION

发明人： Taewoo LEE ,  Jiwon RYU ,  Eun Ji IM

IPC分类号： C12N15/113 ,  A61P35/00

摘要： The present invention relates to a double-helix oligonucleotide construct comprising a double-stranded miRNA and a composition for preventing or treating cancer comprising the same. More particularly, the present invention relates to a double-helix oligonucleotide construct comprising miR-544a characterized by a method that effectively inhibits the proliferation of cancer cells or induces a voluntary death of cancer cells, and an anticancer composition comprising the construct.

公开(公告)号：US20240076672A1

公开(公告)日：2024-03-07

申请号：US18478014

申请日：2023-09-29

申请人： BIONEER CORPORATION

发明人： Taewoo LEE ,  Jiwon RYU ,  Eun Ji IM

IPC分类号： C12N15/113 ,  A61P35/00

CPC分类号： C12N15/1136 ,  A61P35/00 ,  C12N2310/141 ,  C12N2310/50

摘要： The present invention relates to a double-helix oligonucleotide construct comprising a double-stranded miRNA and a composition for preventing or treating cancer comprising the same. More particularly, the present invention relates to a double-helix oligonucleotide construct comprising miR-544a characterized by a method that effectively inhibits the proliferation of cancer cells or induces a voluntary death of cancer cells, and an anticancer composition comprising the construct.