公开(公告)号：US20190262429A1

公开(公告)日：2019-08-29

申请号：US16270302

申请日：2019-02-07

Applicant: BIOVERATIV THERAPEUTICS INC.

Inventor： Jennifer A. DUMONT ,  Susan LOW ,  Alan J. BITONTI ,  Glenn PIERCE ,  Alvin LUK ,  Haiyan JIANG ,  Byron MCKINNEY ,  Matt OTTMER ,  Jurg SOMMER ,  Karen NUGENT ,  Lian LI ,  Robert PETERS

IPC: A61K38/37 ,  A61K47/64 ,  C07K14/755 ,  A61K47/68 ,  C07K16/46

Abstract: The present invention provides methods of administering Factor VIII; methods of administering chimeric and hybrid polypeptides comprising Factor VIII; chimeric and hybrid polypeptides comprising Factor VIII: polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.

公开(公告)号：US20210220476A1

公开(公告)日：2021-07-22

申请号：US17112280

申请日：2020-12-04

Applicant: Bioverativ Therapeutics Inc.

Inventor： Jennifer A. DUMONT ,  Susan LOW ,  Alan J. BITONTI ,  Glenn PIERCE ,  Alvin LUK ,  Haiyan JIANG ,  Byron MCKINNEY ,  Matt OTTMER ,  Jurg SOMMER ,  Karen NUGENT ,  Lian LI ,  Robert T. PETERS

IPC: A61K47/68 ,  A61K47/60 ,  A61K38/37 ,  C07K14/755 ,  G01N33/86

Abstract: The present invention provides methods of administering Factor VIII (processed FVIII, single chain FVIII, or a combination thereof); methods of administering chimeric and hybrid polypeptides comprising Factor VIII; chimeric and hybrid polypeptides comprising Factor VIII; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.

公开(公告)号：US20180360982A1

公开(公告)日：2018-12-20

申请号：US15991629

申请日：2018-05-29

Applicant: Bioverativ Therapeutics Inc.

Inventor： Jennifer A. DUMONT ,  Susan LOW ,  Alan J. BITONTI ,  Glenn PIERCE ,  Alvin LUK ,  Haiyan JIANG ,  Byron MCKINNEY ,  Matt OTTMER ,  Jurg SOMMER ,  Karen NUGENT ,  Lian LI ,  Robert T. PETERS

IPC: A61K47/68 ,  A61K47/60 ,  G01N33/86 ,  A61K38/37 ,  C07K14/755

Abstract: The present invention provides methods of administering Factor VIII (processed FVIII, single chain FVIII, or a combination thereof); methods of administering chimeric and hybrid polypeptides comprising Factor VIII; chimeric and hybrid polypeptides comprising Factor VIII; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.

公开(公告)号：US20220265780A1

公开(公告)日：2022-08-25

申请号：US17587941

申请日：2022-01-28

Applicant: BIOVERATIV THERAPEUTICS INC.

Inventor： Jennifer A. DUMONT ,  Susan LOW ,  Alan J. BITONTI ,  Glenn PIERCE ,  Alvin LUK ,  Haiyan JIANG ,  Byron MCKINNEY ,  Matt OTTMER ,  Jurg SOMMER ,  Karen NUGENT ,  Lian LI ,  Robert PETERS

IPC: A61K38/37 ,  A61K47/64 ,  A61K47/68 ,  C07K14/755 ,  C07K16/46

Abstract: The present invention provides methods of administering Factor VIII; methods of administering chimeric and hybrid polypeptides comprising Factor VIII; chimeric and hybrid polypeptides comprising Factor VIII; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.