公开(公告)号：US20210277378A1

公开(公告)日：2021-09-09

申请号：US17152239

申请日：2021-01-19

Applicant: BIOVERATIV THERAPEUTICS INC.

Inventor： Volker SCHELLENBERGER ,  Willem P. STEMMER ,  Nathan C. GEETHING ,  Wayne TO ,  Joshua SILVERMAN ,  Chia-wei WANG ,  Benjamin SPINK

IPC: C12N9/64 ,  C07K14/00

Abstract: The present invention relates to compositions comprising factor IX coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of coagulation factor-related diseases, disorders, and conditions.