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公开(公告)号：US20180334501A1
公开(公告)日：2018-11-22
申请号：US16019670
申请日：2018-06-27
发明人： Kirsten Arndt-Schmitz , Alix Berton , Michael Chadham Nivens , Karsten Quast , Marco Schlepuetz , Sudha Visvanathan
IPC分类号： C07K16/24 , C07K16/46 , A61K39/395 , A61K39/00
CPC分类号： C07K16/244 , A61K39/39591 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K16/461 , C07K2317/24 , C07K2317/565 , C07K2317/94
摘要： This invention generally relates to methods for the treatment of respiratory diseases, such as asthma, utilizing anti-IL-23A antibodies.
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公开(公告)号：US20170157246A1
公开(公告)日：2017-06-08
申请号：US15327144
申请日：2015-07-23
发明人： Sudha Visvanathan , Patrick BAUM , Oliver KLEINER , Ulrich KUNZ
IPC分类号： A61K39/395 , G01N33/53
CPC分类号： A61K39/3955 , A61K2121/00 , C12Q1/6883 , C12Q2600/106 , C12Q2600/158 , G01N33/53 , G01N33/5308 , G01N33/6863 , G01N33/6869
摘要： This invention generally relates to biomarkers useful in the treatment of IL-23 related diseases, in particular inflammatory diseases such as psoriasis. The invention also relates to methods of using the biomarkers disclosed herein, for example in therapies utilizing IL-23 antagonists.
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公开(公告)号：US12098207B2
公开(公告)日：2024-09-24
申请号：US17376233
申请日：2021-07-15
IPC分类号： C07K16/28 , A61K39/395 , A61P17/00 , A61K39/00
CPC分类号： C07K16/2866 , A61K39/3955 , A61P17/00 , A61K2039/505 , C07K2317/24 , C07K2317/565 , C07K2317/76
摘要： The present invention provides methods for treating, preventing or ameliorating a neutrophilic dermatosis. The methods of the present invention include administering to a patient suffering from a neutrophilic dermatosis a pharmaceutical composition including an anti-interleukin-36 receptor (anti-IL-36R) antibody.
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公开(公告)号：US10507241B2
公开(公告)日：2019-12-17
申请号：US15327144
申请日：2015-07-23
发明人： Sudha Visvanathan , Patrick Baum , Oliver Kleiner , Ulrich Kunz
IPC分类号： C12Q1/6883 , A61K39/395 , G01N33/68 , G01N33/53
摘要： This invention generally relates to biomarkers useful in the treatment of IL-23 related diseases, in particular inflammatory diseases such as psoriasis. The invention also relates to methods of using the biomarkers disclosed herein, for example in therapies utilizing IL-23 antagonists.
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公开(公告)号：US20230049147A1
公开(公告)日：2023-02-16
申请号：US17819327
申请日：2022-08-12
发明人： Jay FINE , Marc Kaestle , Janine Lamar , David Lamb , Meera Ramanujam , Sudha Visvanathan
IPC分类号： C07K16/28 , A61K45/06 , A61P1/00 , A61P11/00 , A61K39/395
摘要： The present invention provides methods for treating, preventing or ameliorating a fibrotic condition. The methods of the present invention include administering to a patient suffering from a fibrotic condition a therapeutically effective amount an anti-interleukin-36 receptor (anti-IL-36R) antibody.
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公开(公告)号：US20200308271A1
公开(公告)日：2020-10-01
申请号：US16724225
申请日：2019-12-21
发明人： Patrick BAUM , Mary Ruth Flack , Annette Bettina Galler , Bojan Lalovic , Kaori Maino , Steven John Padula , Paul Scholl , Koji Sha , Sudha Visvanathan
IPC分类号： C07K16/24 , A61K39/395 , A61P17/06 , C12Q1/6883
摘要： This invention generally relates to methods for the treatment of IL-23 related diseases, in particular inflammatory diseases, such as psoriasis or psoriatic arthritis, utilizing anti-IL-23A antibodies.
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公开(公告)号：US20180105588A1
公开(公告)日：2018-04-19
申请号：US15729940
申请日：2017-10-11
IPC分类号： C07K16/24
CPC分类号： C07K16/244 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K2317/90 , C12Q2600/00
摘要： This invention generally relates to methods for the treatment of IL-23 related diseases, in particular inflammatory diseases, such as Crohn's Disease, utilizing anti-IL-23A antibodies.
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公开(公告)号：US20200376117A1
公开(公告)日：2020-12-03
申请号：US16709055
申请日：2019-12-10
发明人： Sudha Visvanathan , Patrick Baum , Oliver Kleiner , Ulrich Kunz
IPC分类号： A61K39/395 , G01N33/68 , C12Q1/6883 , G01N33/53
摘要： This invention generally relates to biomarkers useful in the treatment of IL-23 related diseases, in particular inflammatory diseases such as psoriasis. The invention also relates to methods of using the biomarkers disclosed herein, for example in therapies utilizing IL-23 antagonists.
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公开(公告)号：US20180009887A1
公开(公告)日：2018-01-11
申请号：US15686365
申请日：2017-08-25
发明人： Kirsten Arndt-Schmitz , Alix Berton , Michael Chadham Nivens , Karsten Quast , Marco Schlepuetz , Sudha Visvanathan
IPC分类号： C07K16/24 , A61K39/395 , C07K16/46 , A61K39/00
CPC分类号： C07K16/244 , A61K39/39591 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K16/461 , C07K2317/24 , C07K2317/565 , C07K2317/94
摘要： This invention generally relates to methods for the treatment of respiratory diseases, such as asthma, utilizing anti-IL-23A antibodies.
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