公开(公告)号：US10507241B2

公开(公告)日：2019-12-17

申请号：US15327144

申请日：2015-07-23

申请人： BOEHRINGER INGELHEIM INTERNATIONAL GMBH

发明人： Sudha Visvanathan ,  Patrick Baum ,  Oliver Kleiner ,  Ulrich Kunz

IPC分类号： C12Q1/6883 ,  A61K39/395 ,  G01N33/68 ,  G01N33/53

摘要： This invention generally relates to biomarkers useful in the treatment of IL-23 related diseases, in particular inflammatory diseases such as psoriasis. The invention also relates to methods of using the biomarkers disclosed herein, for example in therapies utilizing IL-23 antagonists.

公开(公告)号：US20200376117A1

公开(公告)日：2020-12-03

申请号：US16709055

申请日：2019-12-10

申请人： BOEHRINGER INGELHEIM INTERNATIONAL GMBH

发明人： Sudha Visvanathan ,  Patrick Baum ,  Oliver Kleiner ,  Ulrich Kunz

IPC分类号： A61K39/395 ,  G01N33/68 ,  C12Q1/6883 ,  G01N33/53

摘要： This invention generally relates to biomarkers useful in the treatment of IL-23 related diseases, in particular inflammatory diseases such as psoriasis. The invention also relates to methods of using the biomarkers disclosed herein, for example in therapies utilizing IL-23 antagonists.