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公开(公告)号：US20170182339A1
公开(公告)日：2017-06-29
申请号：US15456266
申请日：2017-03-10
发明人： Walter William Wurster , Michael Allen Gustafson , Elaine Patrice Pelletier , Richard Alan Waltz
CPC分类号： A61N7/02 , A61B8/4227 , A61B90/11 , A61N7/00 , A61N2007/0091
摘要： A focused ultrasonic transducer navigation system attaches to a patient and includes a housing that contains an ultrasonic device. An alignment system moves the housing, and moves the ultrasonic device within the housing, so a focal point of ultrasonic energy from the ultrasonic device is aligned in x, y, and z planes with a target location in the patient. The alignment system realigns the focal point of the ultrasonic device with the same patient target location over multiple therapy sessions eliminating repeated use of an MRI system for repeatedly realigning the ultrasonic device.
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公开(公告)号：US09061133B2
公开(公告)日：2015-06-23
申请号：US13728392
申请日：2012-12-27
发明人： Walter William Wurster , Michael Allen Gustafson , Elaine Patrice Pelletier , Richard Alan Waltz
CPC分类号： A61N7/02 , A61B8/4227 , A61B90/11 , A61N7/00 , A61N2007/0091
摘要： A focused ultrasonic transducer navigation system attaches to a patient and includes a housing that contains an ultrasonic device. An alignment system moves the housing, and moves the ultrasonic device within the housing, so a focal point of ultrasonic energy from the ultrasonic device is aligned in x, y, and z planes with a target location in the patient. The alignment system realigns the focal point of the ultrasonic device with the same patient target location over multiple therapy sessions eliminating repeated use of an MRI system for repeatedly realigning the ultrasonic device.
摘要翻译： 聚焦的超声波换能器导航系统附接到患者并且包括容纳超声装置的壳体。 对准系统移动壳体并使超声波装置移动到壳体内，使得来自超声波装置的超声波能量焦点在x，y和z平面上与患者中的目标位置对齐。 对准系统通过多个治疗会话使超声波装置的焦点与相同的患者目标位置重新对准，从而消除重复使用MRI系统以重复重新调整超声波装置。
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公开(公告)号：US20140378874A1
公开(公告)日：2014-12-25
申请号：US14478323
申请日：2014-09-05
发明人： Walter William Wurster , Michael Allen Gustafson , Elaine Patrice Pelletier , Richard Alan Waltz
CPC分类号： A61N7/02 , A61B8/4227 , A61B90/11 , A61N7/00 , A61N2007/0091
摘要： A focused ultrasonic transducer navigation system attaches to a patient and includes a housing that contains an ultrasonic device. An alignment system moves the housing, and moves the ultrasonic device within the housing, so a focal point of ultrasonic energy from the ultrasonic device is aligned in x, y, and z planes with a target location in the patient. The alignment system realigns the focal point of the ultrasonic device with the same patient target location over multiple therapy sessions eliminating repeated use of an MRI system for repeatedly realigning the ultrasonic device.
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公开(公告)号：US10792519B2
公开(公告)日：2020-10-06
申请号：US15456266
申请日：2017-03-10
发明人： Walter William Wurster , Michael Allen Gustafson , Elaine Patrice Pelletier , Richard Alan Waltz
摘要： A focused ultrasonic transducer navigation system attaches to a patient and includes a housing that contains an ultrasonic device. An alignment system moves the housing, and moves the ultrasonic device within the housing, so a focal point of ultrasonic energy from the ultrasonic device is aligned in x, y, and z planes with a target location in the patient. The alignment system realigns the focal point of the ultrasonic device with the same patient target location over multiple therapy sessions eliminating repeated use of an MRI system for repeatedly realigning the ultrasonic device.
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5.发明授权公开(公告)号：US10974078B2
公开(公告)日：2021-04-13
申请号：US15842771
申请日：2017-12-14
摘要： Ultrasonic energy is used for treating degenerative dementia. A focal point of an ultrasonic transducer beam is directed at a target area of the brain to promote removal of substances that accumulate in the interstitial pathways that are at least partially responsible for the degenerative dementia. In one example, the target area of the brain may comprise the hippocampus and the degenerative dementia may be Alzheimer's disease. The ultrasonic beam may stimulate brain tissue at a frequency that corresponds to a naturally occurring deep sleep burst frequency of neurons and subsequent astrocyte activation patterns that drive a convective process responsible for brain solute disposal. For example, the transducer may generate a burst frequency of between 1-4 hertz to stimulate deep sleep brain functions that help remove amyloid plaque.
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公开(公告)号：US09630029B2
公开(公告)日：2017-04-25
申请号：US14478323
申请日：2014-09-05
发明人： Walter William Wurster , Michael Allen Gustafson , Elaine Patrice Pelletier , Richard Alan Waltz
CPC分类号： A61N7/02 , A61B8/4227 , A61B90/11 , A61N7/00 , A61N2007/0091
摘要： A focused ultrasonic transducer navigation system attaches to a patient and includes a housing that contains an ultrasonic device. An alignment system moves the housing, and moves the ultrasonic device within the housing, so a focal point of ultrasonic energy from the ultrasonic device is aligned in x, y, and z planes with a target location in the patient. The alignment system realigns the focal point of the ultrasonic device with the same patient target location over multiple therapy sessions eliminating repeated use of an MRI system for repeatedly realigning the ultrasonic device.
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7.发明授权公开(公告)号：US11766576B2
公开(公告)日：2023-09-26
申请号：US17193087
申请日：2021-03-05
CPC分类号： A61N7/00 , A61B8/488 , A61N7/02 , A61B8/0808 , A61B8/4227 , A61B90/11 , A61N2007/0026 , A61N2007/0091
摘要： Ultrasonic energy is used for treating degenerative dementia. A focal point of an ultrasonic transducer beam is directed at a target area of the brain to promote removal of substances that accumulate in the interstitial pathways that are at least partially responsible for the degenerative dementia. In one example, the target area of the brain may comprise the hippocampus and the degenerative dementia may be Alzheimer's disease. The ultrasonic beam may stimulate brain tissue at a frequency that corresponds to a naturally occurring deep sleep burst frequency of neurons and subsequent astrocyte activation patterns that drive a convective process responsible for brain solute disposal. For example, the transducer may generate a burst frequency of between 1-4 hertz to stimulate deep sleep brain functions that help remove amyloid plaque.
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公开(公告)号：US11311748B2
公开(公告)日：2022-04-26
申请号：US16723752
申请日：2019-12-20
摘要： A stereotactic frame includes a vertical column that extends up from a base. A first laterally extending support arm extends from a first side of the column and a second laterally extending support arm extends from a second side of the column. One of the first or second support arms may include a transducer assembly. The transducer assembly may move a focal point of the transducer in different lateral and longitudinal horizontal positions and different vertical positions. The transducer assembly also may move the focal point of the transducer beam into different pivoting angled positions. The stereotactic frame applies repeatable ultrasonic energy to targets inside a patient without using invasive attachment procedures and without having to repeatedly use expensive magnetic resonance imaging (MRI) machines.
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公开(公告)号：US10512794B2
公开(公告)日：2019-12-24
申请号：US15382351
申请日：2016-12-16
摘要： A stereotactic frame includes a vertical column that extends up from a base. A first laterally extending support arm extends from a first side of the column and a second laterally extending support arm extends from a second side of the column. One of the first or second support arms may include a transducer assembly. The transducer assembly may move a focal point of the transducer in different lateral and longitudinal horizontal positions and different vertical positions. The transducer assembly also may move the focal point of the transducer beam into different pivoting angled positions. The stereotactic frame applies repeatable ultrasonic energy to targets inside a patient without using invasive attachment procedures and without having to repeatedly use expensive magnetic resonance imaging (MRI) machines.
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公开(公告)号：US20140188011A1
公开(公告)日：2014-07-03
申请号：US13728392
申请日：2012-12-27
发明人： Walter William Wurster , Michael Allen Gustafson , Elaine Patrice Pelletier , Richard Alan Waltz
IPC分类号： A61N7/00
CPC分类号： A61N7/02 , A61B8/4227 , A61B90/11 , A61N7/00 , A61N2007/0091
摘要： A focused ultrasonic transducer navigation system attaches to a patient and includes a housing that contains an ultrasonic device. An alignment system moves the housing, and moves the ultrasonic device within the housing, so a focal point of ultrasonic energy from the ultrasonic device is aligned in x, y, and z planes with a target location in the patient. The alignment system realigns the focal point of the ultrasonic device with the same patient target location over multiple therapy sessions eliminating repeated use of an MRI system for repeatedly realigning the ultrasonic device.
摘要翻译： 聚焦的超声波换能器导航系统附接到患者并且包括容纳超声装置的壳体。 对准系统移动壳体并使超声波装置移动到壳体内，使得来自超声波装置的超声波能量焦点在x，y和z平面上与患者中的目标位置对齐。 对准系统通过多个治疗会话使超声波装置的焦点与相同的患者目标位置重新对准，从而消除重复使用MRI系统以重复重新调整超声波装置。
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