公开(公告)号：US20210163443A1

公开(公告)日：2021-06-03

申请号：US17108024

申请日：2020-12-01

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Pravin Sudhakar Shirude ,  Satheesh Kesavan Nair ,  Ramesh Kumar Sistla ,  Ashit K. Ganguly ,  Ramakanth Sarabu

IPC: C07D401/06 ,  C07D401/14 ,  C07D405/14 ,  C07D417/14

Abstract: Disclosed are compounds of Formula I, and pharmaceutically acceptable salts thereof: Also disclosed are pharmaceutical compositions thereof as well as methods for using the compounds in treating a variety of diseases such as, for example, autoimmune diseases, dry eye syndrome, fibrosis, scar formation, angiogenesis, ischemic damage, inflammatory diseases, cancers, musculoskeletal diseases, cardiovascular diseases, transplant rejection, multiple sclerosis, systemic sclerosis and neurodegenerative diseases.