公开(公告)号：US12037323B2

公开(公告)日：2024-07-16

申请号：US17052232

申请日：2019-05-02

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Christine M. Tarby ,  Derek J. Norris ,  Julian C. Lo ,  Vijay T. Ahuja ,  Steven P. Seitz ,  Ashvinikumar V. Gavai ,  John S. Tokarski ,  Mohini Rajasagi ,  Michael Wichroski ,  Matthias Broekema

IPC: C07D401/14 ,  C07D405/14 ,  C07D417/14 ,  C07D471/04

CPC classification number: C07D401/14 ,  C07D405/14 ,  C07D417/14 ,  C07D471/04

Abstract: The invention relates generally to compounds that are Mer-Ax1 inhibitors, pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.

公开(公告)号：US20230339891A1

公开(公告)日：2023-10-26

申请号：US17052232

申请日：2019-05-02

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Christine M. Tarby ,  Derek J. Norris ,  Julian C. Lo ,  Vijay T. Ahuja ,  Steven P. Seitz ,  Ashvinikumar V. Gavai ,  John S. Tokarski ,  Mohini Rajasagi ,  Michael Wichroski ,  Matthias Broekema

IPC: C07D401/14 ,  C07D417/14 ,  C07D471/04 ,  C07D405/14

CPC classification number: C07D401/14 ,  C07D417/14 ,  C07D471/04 ,  C07D405/14

Abstract: The invention relates generally to compounds that are Mer-Ax1 inhibitors, pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.