公开(公告)号：US20230250063A1

公开(公告)日：2023-08-10

申请号：US18004722

申请日：2021-07-08

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： James A. Johnson ,  Zulan Pi ,  Nicholas R. Wurtz ,  Joanne M. Smallheer ,  Meriah Neissel Valente ,  Ellen K. Kick ,  Charles G. Clark ,  Pravin Sudhaka Shirude ,  Balaji Kumar Seshadri ,  Amit Kumar Chattopadhyay

IPC: C07D231/50 ,  C07D405/14 ,  C07D401/14 ,  C07D451/02 ,  C07D413/14 ,  C07D401/04

CPC classification number: C07D231/50 ,  C07D405/14 ,  C07D401/14 ,  C07D451/02 ,  C07D413/14 ,  C07D401/04

Abstract: The disclosure relates to compounds of formula I, which are formyl peptide 2 (FPR2) receptor agonists. The disclosure also provides compositions and methods of using the compounds, for example, for the treatment of atherosclerosis, heart failure, chronic obstructive pulmonary disease (COPD), and related diseases.