公开(公告)号：US20150126752A1

公开(公告)日：2015-05-07

申请号：US14407509

申请日：2013-06-12

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Sarah Evelyn Steinhardt ,  Martin D. Eastgate

IPC: C07D307/33

CPC classification number: C07D307/33

Abstract: Disclosed is a process to prepare a ribonolactone compound of Formula (I): comprising the step of reacting a fructosamine compound of Formula (II): in the presence of a calcium salt and a base in a nonaqueous reaction medium, to provide said ribonolactone compound of Formula (I).

Abstract translation: 公开了制备式（I）的核糖内酯化合物的方法：包括使式（II）的果糖胺化合物在钙盐和碱的存在下在非水反应介质中反应的步骤，以提供所述核糖内酯化合物 的式（I）。