公开(公告)号：US20140081050A1

公开(公告)日：2014-03-20

申请号：US14001892

申请日：2012-02-14

申请人： Bala Subramaniam ,  Raghunath V. Chaudhari ,  Bibhas R. Sarkar

发明人： Bala Subramaniam ,  Raghunath V. Chaudhari ,  Bibhas R. Sarkar

IPC分类号： C07C45/50

CPC分类号： C07C45/505 ,  B01J19/24 ,  B01J31/1683 ,  B01J31/2404 ,  B01J31/4046 ,  B01J31/4053 ,  B01J31/4061 ,  B01J2231/321 ,  B01J2531/822 ,  C07C45/50 ,  C07C47/02 ,  Y02P20/584 ,  C07C47/19

摘要： Allyl alcohol, particularly from biobased sources such as glycerol, is hydroformylated to products including 4-hydroxybutyraldehyde and 4-hydroxy-2-methylpropionaldehyde by forming a homogeneous reaction mixture including allyl alcohol, a rhodium-based hydroformylation catalyst and a near critical liquefiable petroleum gas or mixture of such gases, reacting the near critical liquefiable petroleum gas (or gas mixture)-expanded allyl alcohol substrate with carbon monoxide and with hydrogen in the presence of the catalyst, and recovering substantially all of the petroleum gas or gases overhead by reducing the pressure and degassing the product mixture. Dense propane is especially useful as a single inert solvent/diluent, and substantially no other solvent/diluent is needed.

摘要翻译： 烯丙醇，特别是生物碱源如甘油，通过形成包括烯丙醇，铑基加氢甲酰化催化剂和近临界液化石油气的均匀反应混合物，加氢甲酰化成包括4-羟基丁醛和4-羟基-2-甲基丙醛的产物 或这些气体的混合物，在催化剂存在下，将近临界液化石油气（或气体混合物） - 膨胀的烯丙醇底物与一氧化碳和氢气反应，并通过减少 压力和脱气产物混合物。 浓缩丙烷作为单一惰性溶剂/稀释剂是特别有用的，并且基本上不需要其它溶剂/稀释剂。