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公开(公告)号：US08962005B2
公开(公告)日：2015-02-24
申请号：US14078156
申请日：2013-11-12
CPC分类号： A61K9/4825 , A61K9/4816 , A61K9/4833 , A61K35/60 , A61K47/10 , A61K47/36 , A61K47/42
摘要： Gastric resistant film-forming compositions are described herein. The composition comprises a gastric resistant natural polymer, a film-forming natural polymer, and optionally a gelling agent. Suitable gastric resistant natural polymers include polysaccharides such as pectin and pectin-like polymers. The film-forming composition can be used to prepare soft or hard shell gelatin capsules which can encapsulate a liquid or semi-solid fill material or a solid tablet (Softlet®) comprising an active agent and one or more pharmaceutically acceptable excipients. Alternatively, the composition can be administered as a liquid with an active agent dissolved or dispersed in the composition. The compositions are not only gastric resistant but may also prevent gastric reflux associated with odor causing liquids, such as fish oil or garlic oil, encapsulated in a unit dosage form and esophageal irritation due to the reflux of irritant drugs delivered orally.
摘要翻译： 本文描述了耐胃成膜组合物。 该组合物包含耐胃天然聚合物，成膜天然聚合物和任选的胶凝剂。 合适的耐胃天然聚合物包括多糖如果胶和果胶样聚合物。 成膜组合物可用于制备可包封液体或半固体填充材料的软壳或硬壳明胶胶囊或包含活性剂和一种或多种药学上可接受的赋形剂的固体片剂（Softlet）。 或者，组合物可以以溶解或分散在组合物中的活性剂作为液体施用。 组合物不仅具有抗胃肠道功能，而且还可以防止与气味引起的胃反流相关，所述气味引起液体，例如以单位剂量形式包封的鱼油或大蒜油，以及因口服递送的刺激性药物的反流引起的食管刺激。
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公开(公告)号：US20140072625A1
公开(公告)日：2014-03-13
申请号：US14078156
申请日：2013-11-12
CPC分类号： A61K9/4825 , A61K9/4816 , A61K9/4833 , A61K35/60 , A61K47/10 , A61K47/36 , A61K47/42
摘要： Gastric resistant film-forming compositions are described herein. The composition comprises a gastric resistant natural polymer, a film-forming natural polymer, and optionally a gelling agent. Suitable gastric resistant natural polymers include polysaccharides such as pectin and pectin-like polymers. The film-forming composition can be used to prepare soft or hard shell gelatin capsules which can encapsulate a liquid or semi-solid fill material or a solid tablet (Softlet®) comprising an active agent and one or more pharmaceutically acceptable excipients. Alternatively, the composition can be administered as a liquid with an active agent dissolved or dispersed in the composition. The compositions are not only gastric resistant but may also prevent gastric reflux associated with odor causing liquids, such as fish oil or garlic oil, encapsulated in a unit dosage form and esophageal irritation due to the reflux of irritant drugs delivered orally.
摘要翻译： 本文描述了耐胃成膜组合物。 该组合物包含耐胃天然聚合物，成膜天然聚合物和任选的胶凝剂。 合适的耐胃天然聚合物包括多糖如果胶和果胶样聚合物。 成膜组合物可用于制备可包封液体或半固体填充材料的软壳或硬壳明胶胶囊或包含活性剂和一种或多种药学上可接受的赋形剂的固体片剂（Softlet）。 或者，组合物可以以溶解或分散在组合物中的活性剂作为液体施用。 组合物不仅具有抗胃肠道功能，而且还可以防止与气味引起的胃反流相关，所述气味引起液体，例如以单位剂量形式包封的鱼油或大蒜油，以及因口服递送的刺激性药物的反流引起的食管刺激。
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公开(公告)号：US09192582B2
公开(公告)日：2015-11-24
申请号：US14507327
申请日：2014-10-06
CPC分类号： A61K9/4825 , A61K9/4816 , A61K9/4833 , A61K35/60 , A61K47/10 , A61K47/36 , A61K47/42
摘要： Gastric resistant film-forming compositions are described herein. The composition comprises a gastric resistant natural polymer, a film-forming natural polymer, and optionally a gelling agent. Suitable gastric resistant natural polymers include polysaccharides such as pectin and pectin-like polymers. The film-forming composition can be used to prepare soft or hard shell gelatin capsules which can encapsulate a liquid or semi-solid fill material or a solid tablet (Softlet®) comprising an active agent and one or more pharmaceutically acceptable excipients. Alternatively, the composition can be administered as a liquid with an active agent dissolved or dispersed in the composition. The compositions are not only gastric resistant but may also prevent gastric reflux associated with odor causing liquids, such as fish oil or garlic oil, encapsulated in a unit dosage form and esophageal irritation due to the reflux of irritant drugs delivered orally.
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公开(公告)号：US20150352054A9
公开(公告)日：2015-12-10
申请号：US13693332
申请日：2012-12-04
CPC分类号： A61K9/4825 , A23L29/284 , A23P10/30 , A23V2002/00 , A61K9/4816 , A61K9/4833 , A61K9/4858 , A61K9/4866 , A61K9/70 , A61K31/4402 , A61K31/4439 , A61K31/5415 , A61K31/616 , A61K31/663
摘要： A gel mass is provided that is useful in manufacturing enteric soft or hard capsules, or enteric tablets without coating.
摘要翻译： 提供了可用于制造肠溶软或硬胶囊或不包衣的肠溶片剂的凝胶质量。
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公开(公告)号：US20150024044A1
公开(公告)日：2015-01-22
申请号：US14507327
申请日：2014-10-06
CPC分类号： A61K9/4825 , A61K9/4816 , A61K9/4833 , A61K35/60 , A61K47/10 , A61K47/36 , A61K47/42
摘要： Gastric resistant film-forming compositions are described herein. The composition comprises a gastric resistant natural polymer, a film-forming natural polymer, and optionally a gelling agent. Suitable gastric resistant natural polymers include polysaccharides such as pectin and pectin-like polymers. The film-forming composition can be used to prepare soft or hard shell gelatin capsules which can encapsulate a liquid or semi-solid fill material or a solid tablet (Softlet®) comprising an active agent and one or more pharmaceutically acceptable excipients. Alternatively, the composition can be administered as a liquid with an active agent dissolved or dispersed in the composition. The compositions are not only gastric resistant but may also prevent gastric reflux associated with odor causing liquids, such as fish oil or garlic oil, encapsulated in a unit dosage form and esophageal irritation due to the reflux of irritant drugs delivered orally.
摘要翻译： 本文描述了耐胃成膜组合物。 该组合物包含耐胃天然聚合物，成膜天然聚合物和任选的胶凝剂。 合适的耐胃天然聚合物包括多糖如果胶和果胶样聚合物。 成膜组合物可用于制备可包封液体或半固体填充材料的软壳或硬壳明胶胶囊或包含活性剂和一种或多种药学上可接受的赋形剂的固体片剂（Softlet）。 或者，组合物可以以溶解或分散在组合物中的活性剂作为液体施用。 组合物不仅具有抗胃肠道功能，而且还可以防止与气味引起的胃反流相关，所述气味引起液体，例如以单位剂量形式包封的鱼油或大蒜油，以及因口服递送的刺激性药物的反流引起的食管刺激。
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公开(公告)号：US20140154311A1
公开(公告)日：2014-06-05
申请号：US13693332
申请日：2012-12-04
CPC分类号： A61K9/4825 , A23L29/284 , A23P10/30 , A23V2002/00 , A61K9/4816 , A61K9/4833 , A61K9/4858 , A61K9/4866 , A61K9/70 , A61K31/4402 , A61K31/4439 , A61K31/5415 , A61K31/616 , A61K31/663
摘要： A gel mass is provided that is useful in manufacturing enteric soft or hard capsules, or enteric tablets without coating.
摘要翻译： 提供了可用于制造肠溶软或硬胶囊或不包衣的肠溶片剂的凝胶质量。
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