-
公开(公告)号:US20130028913A1
公开(公告)日:2013-01-31
申请号:US13513502
申请日:2010-12-01
申请人: Barbara Leuchs , Kathrin Kürschner , Andrea Kuck , Marcus Müller , Silvia Münstermann , Jean Rommelaere
发明人: Barbara Leuchs , Kathrin Kürschner , Andrea Kuck , Marcus Müller , Silvia Münstermann , Jean Rommelaere
CPC分类号: C07K16/081 , C07K2317/76 , G01N33/56983 , G01N2333/015
摘要: Described is an antibody or an antigen binding fragment thereof specifically binding to a full or empty H-1 parvovirus capsid. Such an antibody is useful for various diagnostic and therapeutic methods, e.g., for the detection/therapy of an H-1 parvovirus infection during pregnancy since parvovirus affects about 1 in 400 pregnancies and may cause fetal loss or fetal hydrops.
摘要翻译: 描述了特异性结合完整或空的H-1细小病毒衣壳的抗体或其抗原结合片段。 这种抗体可用于各种诊断和治疗方法,例如用于在怀孕期间检测/治疗H-1细小病毒感染,因为细小病毒在400次怀孕中影响约1次,并可能引起胎儿丧失或胎儿水肿。
-
公开(公告)号:US08828400B2
公开(公告)日:2014-09-09
申请号:US13513502
申请日:2010-12-01
申请人: Barbara Leuchs , Kathrin Kürschner , Andrea Kuck , Marcus Müller , Silvia Münstermann , Jean Rommelaere
发明人: Barbara Leuchs , Kathrin Kürschner , Andrea Kuck , Marcus Müller , Silvia Münstermann , Jean Rommelaere
IPC分类号: A61K39/42 , C07K16/08 , C12Q1/70 , G01N33/569
CPC分类号: C07K16/081 , C07K2317/76 , G01N33/56983 , G01N2333/015
摘要: Described is an antibody or an antigen binding fragment thereof specifically binding to a full or empty H-1 parvovirus capsid. Such an antibody is useful for various diagnostic and therapeutic methods, e.g., for the detection/therapy of an H-1 parvovirus infection during pregnancy since parvovirus affects about 1 in 400 pregnancies and may cause fetal loss or fetal hydrops.
摘要翻译: 描述了特异性结合完整或空的H-1细小病毒衣壳的抗体或其抗原结合片段。 这种抗体可用于各种诊断和治疗方法,例如用于在怀孕期间检测/治疗H-1细小病毒感染,因为细小病毒在400次怀孕中影响约1次,并可能引起胎儿丧失或胎儿水肿。
-