公开(公告)号：US20200276362A1

公开(公告)日：2020-09-03

申请号：US16650956

申请日：2018-03-29

申请人： BARD SHANNON LIMITED

发明人： Guy Tomer ,  Aurelie Benaddi ,  Moriah Anouchi ,  Amir Hadid

IPC分类号： A61L27/52 ,  A61K31/496 ,  A61K31/7036 ,  A61K9/16 ,  A61L27/54 ,  A61L27/48 ,  A61L27/22

摘要： A composition, comprising a hydrogel matrix and microparticles within said matrix, said matrix comprising a cross-linkable protein and a cross-linking agent, wherein said cross-linking agent is able to cross-link said cross-linkable protein, wherein said microparticles comprise a drug.

公开(公告)号：US11998654B2

公开(公告)日：2024-06-04

申请号：US16508356

申请日：2019-07-11

申请人： Bard Shannon Limited

发明人： Gideon Sturlesi ,  Guy Tomer ,  Aurelie Benaddi ,  Mary Hainrichson ,  Amir Hadid ,  Ofer Yatziv

IPC分类号： A61L24/04 ,  A61L24/00

CPC分类号： A61L24/043 ,  A61L24/0036

摘要： A biocompatible material for securing such implantable medical devices, for example by using an adhesive path.

公开(公告)号：US20220331492A1

公开(公告)日：2022-10-20

申请号：US17741358

申请日：2022-05-10

申请人： Bard Shannon Limited

发明人： Guy Tomer ,  Aurelie Benaddi ,  Moriah Anouchi ,  Amir Hadid

IPC分类号： A61L27/52 ,  A61K9/16 ,  A61K31/496 ,  A61K31/7036 ,  A61L27/22 ,  A61L27/48 ,  A61L27/54

摘要： A composition, comprising a hydrogel matrix and microparticles within said matrix, said matrix comprising a cross-linkable protein and a cross-linking agent, wherein said cross-linking agent is able to cross-link said cross-linkable protein, wherein said microparticles comprise a drug.

公开(公告)号：US20220126000A1

公开(公告)日：2022-04-28

申请号：US17520561

申请日：2021-11-05

申请人： Bard Shannon Limited

发明人： Orahn Preiss-Bloom ,  Guy Tomer ,  Amir Hadid ,  Alon Polakewicz ,  Ariel Maizler ,  Denis Kramarenko ,  Daniella Goder ,  Danny Yosufov

IPC分类号： A61L31/10 ,  A61L31/12 ,  A61L31/14 ,  C08L89/00

摘要： A mesh-based composition comprising a cross-linkable protein or polypeptide and one or more cross-linking materials according to at least some embodiments. The mesh-based composition may comprise a self-adhering surgical mesh which requires no additional fixation while at the same time minimizes adhesions. The mesh may be in the form of a composite mesh featuring a foamed composition of the cross-linkable protein and a non-toxic material that induces cross-linking of the cross-linkable protein. The composite mesh may be in a sheet-like form.