公开(公告)号：US20230208045A1

公开(公告)日：2023-06-29

申请号：US18111765

申请日：2023-02-20

申请人： Battelle Memorial Institute

发明人： Eric Scribben ,  Steven M. Heintz ,  Amy M. Heintz ,  Jeffrey L. Ellis ,  John D. Clay ,  Timothy M. Blum

IPC分类号： H01Q21/06 ,  H01Q1/48 ,  H01Q21/24

CPC分类号： H01Q21/062 ,  H01Q1/48 ,  H01Q21/245 ,  H01Q1/243

摘要： Core annular flow is used to enable the subcutaneous delivery of a viscous fluid such as a protein therapeutic formulation. The high-viscosity fluid is surrounded by a low-viscosity fluid, and the low-viscosity fluid lubricates the passage of the high-viscosity fluid. This allows the use of protein formulations that have a higher concentration and a higher viscosity at comparatively reduced injection forces and reduced injection times. Several different embodiments of injection devices that provide core annular flow are described herein.