公开(公告)号：US20220324865A1

公开(公告)日：2022-10-13

申请号：US17055190

申请日：2019-05-10

申请人： Bayer Aktiengesellschaft ,  Bayer Pharma Aktiengesellschaft

发明人： Steffen MUELLER ,  Rudolf SCHOHE-LOOP ,  Nuria ORTEGA HERNANDEZ ,  Frank SUESSMEIER ,  Eloisa JIMENEZ NUNEZ ,  Thomas BRUMBY ,  Niels LINDNER ,  Christoph GERDES ,  Elisabeth POOK ,  Anja BUCHMUELLER ,  Fabienne Zdenka GAUGAZ ,  Dieter LANG ,  Stefanie ZIMMERMANN ,  Alexander Helmut Michael EHRMANN ,  Michael GERISCH ,  Lutz LEHMANN ,  Andreas TIMMERMANN ,  Martina SCHAEFER ,  Georg SCHMIDT ,  Karl-Heinz SCHLEMMER ,  Markus FOLLMANN ,  Elisabeth KERSTEN ,  Vivian WANG ,  Xiang GAO ,  Yafeng WANG

IPC分类号： C07D487/04 ,  A61P7/02

摘要： The invention relates to substituted dihydropyrazolo pyrazine carboxamide derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and diabetes, and also urogenital and ophthalmic disorders.