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公开(公告)号：US20220324865A1
公开(公告)日：2022-10-13
申请号：US17055190
申请日：2019-05-10
发明人： Steffen MUELLER , Rudolf SCHOHE-LOOP , Nuria ORTEGA HERNANDEZ , Frank SUESSMEIER , Eloisa JIMENEZ NUNEZ , Thomas BRUMBY , Niels LINDNER , Christoph GERDES , Elisabeth POOK , Anja BUCHMUELLER , Fabienne Zdenka GAUGAZ , Dieter LANG , Stefanie ZIMMERMANN , Alexander Helmut Michael EHRMANN , Michael GERISCH , Lutz LEHMANN , Andreas TIMMERMANN , Martina SCHAEFER , Georg SCHMIDT , Karl-Heinz SCHLEMMER , Markus FOLLMANN , Elisabeth KERSTEN , Vivian WANG , Xiang GAO , Yafeng WANG
IPC分类号： C07D487/04 , A61P7/02
摘要： The invention relates to substituted dihydropyrazolo pyrazine carboxamide derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and diabetes, and also urogenital and ophthalmic disorders.
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公开(公告)号：US20220144848A1
公开(公告)日：2022-05-12
申请号：US17416274
申请日：2019-12-18
发明人： Susanne ROEHRIG , Sebastian ESSIG , Pascal ELLERBROCK , Sonja ANLAUF , Thomas NEUBAUER , Alexander HILLISCH , Katharina MEIER , Stefan HEITMEIER , Adrian TERSTEEGEN , Martina SCHAFER , Jan STAMPFUSS , Dieter LANG , Eloisa JIMENEZ NUNEZ , Jens ACKERSTAFF , Henrik TELLER , Zengqiang ZOU , Ping LIU , Xianghai MENG , Frank LESSMANN
IPC分类号： C07D491/044
摘要： The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular vascular disorders, preferably thrombotic or thromboembolic disorders and/or thrombotic or thromboembolic complications.
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公开(公告)号：US20160272637A1
公开(公告)日：2016-09-22
申请号：US15032212
申请日：2014-10-28
发明人： Susanne RÖHRIG , Alexander HILLISCH , Julia STRASSBURGER , Stefan HEITMEIER , Martina Victoria SCHMIDT , Karl-Heinz SCHLEMMER , Adrian TERSTEEGEN , Anja BUCHMÜLLER , Christoph GERDES , Martina SCHÄFER , Henrik TELLER , Eloisa JIMENEZ NUNEZ , Hartmut SCHIROK , Jürgen KLAR
IPC分类号： C07D471/04
CPC分类号： C07D471/04 , A61K31/437 , C07D487/04
摘要： The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.
摘要翻译： 本发明涉及取代的氧代吡啶衍生物及其制备方法，以及它们用于制备用于治疗和/或预防疾病，特别是心血管疾病，优选血栓形成或血栓栓塞性疾病，以及眼药水以及眼科疾病的药物的用途 。
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公开(公告)号：US20180194745A1
公开(公告)日：2018-07-12
申请号：US15742063
申请日：2016-07-05
发明人： Eloisa JIMENEZ NUNEZ , Jens ACKERSTAFF , Susanne RÖHRIG , Alexander HILLISCH , Katharina MEIER , Stefan HEITMEIER , Adrian TERSTEEGEN , Jan STAMPFUß , Pascal ELLERBROCK , Daniel MEIBOM , Dieter LANG
IPC分类号： C07D401/10 , C07D401/14 , C07D413/10 , C07D413/14 , A61P7/02
摘要： The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.
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公开(公告)号：US20170298052A1
公开(公告)日：2017-10-19
申请号：US15513988
申请日：2015-09-22
发明人： Susanne RÖHRIG , Eloisa JIMENEZ NUNEZ , Karl-Heinz SCHLEMMER , Adrian TERSTEEGEN , Henrik TELLER , Alexander HILLISCH , Stefan HEITMEIER , Martina Victoria SCHMIDT , Jan STAMPFUß
IPC分类号： C07D413/06 , C07D401/06 , C07D213/69 , C07D405/06 , C07D213/64
CPC分类号： C07D413/06 , A61P7/10 , A61P27/02 , C07D213/64 , C07D213/69 , C07D213/85 , C07D401/06 , C07D401/12 , C07D405/06 , C07D413/12
摘要： The invention relates to substituted oxopyridine derivatives and to processes for preparation thereof, and also to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.
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公开(公告)号：US20230024752A1
公开(公告)日：2023-01-26
申请号：US17504243
申请日：2021-10-18
发明人： Eloisa JIMENEZ NUNEZ , Jens ACKERSTAFF , Susanne ROEHRIG , Alexander HILLISCH , Katharina MEIER , Stefan HEITMEIER , Adrian TERSTEEGEN , Jan STAMPFUSS , Pascal ELLERBROCK , Daniel MEIBOM , Dieter LANG
IPC分类号： C07D401/10 , C07D401/14 , C07D413/14 , C07D413/10 , A61P7/02
摘要： The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.
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7.发明申请Substituted Oxopyridine Derivatives and Use Thereof in the Treatment of Cardiovascular Disorders 有权取代的氧吡啶衍生物及其用途治疗心血管疾病公开(公告)号：US20160052884A1
公开(公告)日：2016-02-25
申请号：US14780925
申请日：2014-03-27
发明人： Susanne RÖHRIG , Alexander HILLISCH , Julia STRAßBURGER , Stefan HEITMEIER , Martina Victoria SCHMIDT , Karl-Heinz SCHLEMMER , Adrian TERSTEEGEN , Anja BUCHMÜLLER , Christoph GERDES , Martina SCHÄFER , Tom KINZEL , Henrik TELLER , Hartmut SCHIROK , Jürgen KLAR , Eloisa JIMENEZ NUNEZ
IPC分类号： C07D213/64 , C07D413/12 , C07D213/84 , C07D409/06 , C07D405/06 , C07D413/14 , C07D417/12 , C07D401/12 , C07D213/69
CPC分类号： C07D405/06 , C07B2200/05 , C07D213/64 , C07D213/69 , C07D213/84 , C07D213/85 , C07D401/12 , C07D409/06 , C07D413/12 , C07D413/14 , C07D417/12
摘要： The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.
摘要翻译： 本发明涉及取代的氧代吡啶衍生物及其制备方法，以及它们用于制备用于治疗和/或预防疾病，特别是心血管疾病，优选血栓形成或血栓栓塞性疾病，以及眼药水以及眼科疾病的药物的用途 。
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公开(公告)号：US20190119213A1
公开(公告)日：2019-04-25
申请号：US15557831
申请日：2016-03-15
发明人： Susanne RÖHRIG , Henrik TELLER , Stefan HEITMEIER , Karl-Heinz SCHLEMMER , Jan STAMPFUß , Alexander HILLISCH , Adrian TERSTEEGEN , Eloisa JIMENEZ NUNEZ
IPC分类号： C07D213/69 , A61K9/20 , A61K9/00 , A61P27/02 , A61P7/02
摘要： The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.
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公开(公告)号：US20180250280A1
公开(公告)日：2018-09-06
申请号：US15757135
申请日：2016-08-30
发明人： Eloisa JIMENEZ NUNEZ , Jens ACKERSTAFF , Pascal ELLERBROCK , Alexander HILLISCH , Katharina MEIER , Stefan HEITMEIER , Adrian TERSTEEGEN , Jan STAMPFUß
IPC分类号： A61K31/4412 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61P1/00 , A61P7/02 , A61P27/02
CPC分类号： A61K31/4412 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61P1/00 , A61P7/02 , A61P27/02 , C07D213/69 , C07D401/12 , C07D403/06 , C07D403/12 , C07D403/14 , C07D405/06 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/14 , C07D487/04
摘要： The invention relates to substituted oxopyridine derivatives and to processes for preparation thereof, and also to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.
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