公开(公告)号：US11793196B2

公开(公告)日：2023-10-24

申请号：US16822279

申请日：2020-03-18

Applicant: Bayer CropScience LP

Inventor： Damian Curtis ,  Kevin Bugg

IPC: A01N37/46 ,  C07K14/32 ,  C12N9/64

CPC classification number: A01N37/46 ,  C07K14/32 ,  C12N9/6424 ,  C07K2319/00 ,  C07K2319/035

Abstract: The present invention relates to a fusion protein having a targeting sequence, exosporium protein, or exosporium protein fragment that targets the fusion protein to the exosporium of a recombinant Bacillus cereus family member and an enzyme having serine protease activity, wherein the enzyme having serine protease activity is from Bacillus firmus or is a variant of such enzyme. The present invention also provides a recombinant Bacillus cereus family member that expresses such fusion protein and exosporium fragments derived from such recombinant Bacillus cereus family member. Methods of using such recombinant Bacillus cereus family members or exosporium fragments derived therefrom for nematode control are also provided.