公开(公告)号：US20210204550A1

公开(公告)日：2021-07-08

申请号：US17055923

申请日：2019-05-14

Applicant: Bayer CropScience LP

Inventor： Andreas GÖRTZ ,  Chad KIMMELSHUE ,  Yan LI ,  Colleen S. TAYLOR ,  Cecilia R. WILSON ,  Kristina FINSETH

IPC: A01N63/25 ,  A01N25/22

Abstract: The present invention relates to a stabilized fungicidal composition comprising: a) a fusaricidin-producing Paenibacillus sp. strain; and b) a stabilizing agent selected from the group consisting of an amine, a quaternary ammonium compound, a salt of phosphate or citrate, a short chain polyol having from 2 to 10 carbon atoms, a urea, and combinations thereof. The present invention also provides agriculturally acceptable stable aqueous formulations comprising a fusaricidin-producing Paenibacillus sp. strain and a stabilizing agent and methods of controlling disease in plants with the fungicidal compositions and aqueous formulations.

公开(公告)号：US20190062370A1

公开(公告)日：2019-02-28

申请号：US16080453

申请日：2017-03-01

Applicant: Bayer CropScience LP

Inventor： Chad KIMMELSHUE ,  Yan LI ,  Colleen S. TAYLOR ,  Hong ZHU

IPC: C07K1/36 ,  C07K7/64 ,  C07K1/30 ,  C12P19/04

Abstract: The present invention provides a method of enriching a lipopeptide in a microbial cell culture, the method comprising mixing an amphiphilic sulfonate and/or an amphiphilic sulfate with the cell culture to induce the formation of aggregates containing the lipopeptide, centrifuging the cell culture to generate a supernatant fraction and a pellet fraction, separating the pellet fraction from the supernatant fraction, and mixing the pellet fraction with a polyoxyethylene glycol alkyl ether to release the lipopeptide from the aggregates. Also provided is a method of purifying an exopolysaccharide from a microbial cell culture, the method comprising mixing an amphiphilic sulfonate and/or an amphiphilic sulfate with the cell culture to induce the formation of aggregates, centrifuging the cell culture to generate a supernatant fraction and a pellet fraction, separating the supernatant fraction from the pellet fraction, adding alcohol to the supernatant fraction to precipitate the exopolysaccharide; and removing the precipitated exopolysaccharide from the supernatant fraction.