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    PAENIBACILLUS STRAINS AND METHODS FOR THEIR USE
    2.
    发明申请
    PAENIBACILLUS STRAINS AND METHODS FOR THEIR USE 有权

    公开(公告)号：US20220151242A1

    公开(公告)日：2022-05-19

    申请号：US17435848

    申请日：2020-03-05

    Applicant: Bayer CropScience LP

    Inventor： Jeremy BEAU ,  Andreas GOERTZ ,  Adam NEWMAN ,  Patrick SCHWIENTEK ,  Colleen S. TAYLOR ,  Donglan TIAN ,  Bjorn A. TRAAG

    IPC: A01N63/25 ,  C12N1/20

    Abstract: The present invention provides a composition comprising a biologically pure culture of a Paenibacillus sp. strain or a cell-free preparation thereof comprising a fusaricidin and a tridecaptin; wherein the fusaricidin is produced with a fusaricidin synthetase gene of fusA encoded by a DNA sequence exhibiting at least 90.5% sequence identity to SEQ ID NO: 3; and the tridecaptin is produced with a nonribosomal peptide synthetase (NRPS) gene of triE encoded by a DNA sequence exhibiting at least 90.0% sequence identity to SEQ ID NO: 7. Also provided are methods of treating an agricultural plant to control a disease and methods of increasing the vigor and/or crop yield of an agricultural plant with the disclosed compositions.

    METHODS OF CONTROLLING ANIMAL PESTS WITH PAENIBACILLUS TERRAE
    3.
    发明申请
    METHODS OF CONTROLLING ANIMAL PESTS WITH PAENIBACILLUS TERRAE 有权

    公开(公告)号：US20220030876A1

    公开(公告)日：2022-02-03

    申请号：US17276267

    申请日：2019-09-18

    Applicant: Bayer CropScience LP

    Inventor： Punita JUNEJA ,  Colleen S. TAYLOR ,  Emily WHITSON-WHENNEN

    IPC: A01N63/20 ,  A01N25/02

    Abstract: The present invention provides a method of controlling animal pests, protecting a useful plant or a part of a useful plant in need of protection from animal pest damage, or protecting a seed or a plant from which the seed grows from damage by animal pests, the method comprising contacting an animal pest, a plant, a plant propagule, a seed of a plant, and/or a locus where a plant is growing or is intended to grow with an effective amount of a composition comprising a biologically pure culture of a Paenibacillus terrae strain or a cell-free preparation thereof.

    NOVEL PAENIBACILLUS STRAIN, ANTIFUNGAL COMPOUNDS, AND METHODS FOR THEIR USE
    6.
    发明申请
    NOVEL PAENIBACILLUS STRAIN, ANTIFUNGAL COMPOUNDS, AND METHODS FOR THEIR USE 有权
    新型PAENIBACILLUS菌株，抗真菌化合物及其使用方法

    公开(公告)号：US20160278388A1

    公开(公告)日：2016-09-29

    申请号：US15078670

    申请日：2016-03-23

    Applicant: Bayer CropScience LP

    Inventor： Jeremy BEAU ,  Daniel M. JOO ,  Patrick SCHWIENTEK ,  Colleen S. TAYLOR ,  Bjorn A. TRAAG

    IPC: A01N63/02 ,  C12N9/90

    CPC classification number: A01N63/02 ,  A01N63/00 ,  C07K14/195 ,  C12N9/90 ,  C12N9/93 ,  C12R1/01

    Abstract: The present invention relates to a composition comprising a biologically pure culture of a fungicidal Paenibacillus sp. strain comprising a variant fusaricidin synthetase lacking a functional adenylation domain in the third module. The present invention also provides a composition comprising a biologically pure culture of a fungicidal Paenibacillus sp. strain or a cell-free extract thereof comprising at least one Paeniserine and at least one Paeniprolixin. Also provided are isolated compounds and methods of treating a plant to control a plant disease with the disclosed compositions and compounds.

    Abstract translation: 本发明涉及包含杀真菌Paenibacillus sp。的生物纯培养物的组合物。 菌株，其包含在第三个模块中缺少功能性腺苷酸化结构域的变体fusaricidin合成酶。 本发明还提供一种组合物，其包含生物纯的杀真菌Paenibacillus sp。 菌株或其无细胞提取物，其包含至少一种Paeniserine和至少一种Paeniprolixin。 还提供了分离的化合物和用所公开的组合物和化合物处理植物以控制植物病害的方法。

    STABILIZED FUNGICIDAL COMPOSITION
    7.
    发明申请
    STABILIZED FUNGICIDAL COMPOSITION 有权

    公开(公告)号：US20210204550A1

    公开(公告)日：2021-07-08

    申请号：US17055923

    申请日：2019-05-14

    Applicant: Bayer CropScience LP

    Inventor： Andreas GÖRTZ ,  Chad KIMMELSHUE ,  Yan LI ,  Colleen S. TAYLOR ,  Cecilia R. WILSON ,  Kristina FINSETH

    IPC: A01N63/25 ,  A01N25/22

    Abstract: The present invention relates to a stabilized fungicidal composition comprising: a) a fusaricidin-producing Paenibacillus sp. strain; and b) a stabilizing agent selected from the group consisting of an amine, a quaternary ammonium compound, a salt of phosphate or citrate, a short chain polyol having from 2 to 10 carbon atoms, a urea, and combinations thereof. The present invention also provides agriculturally acceptable stable aqueous formulations comprising a fusaricidin-producing Paenibacillus sp. strain and a stabilizing agent and methods of controlling disease in plants with the fungicidal compositions and aqueous formulations.

    METHOD OF PURIFYING ANTIFUNGAL COMPOUNDS AND EXOPOLYSACCHARIDES FROM A MICROBIAL CELL CULTURE
    9.
    发明申请
    METHOD OF PURIFYING ANTIFUNGAL COMPOUNDS AND EXOPOLYSACCHARIDES FROM A MICROBIAL CELL CULTURE 审中-公开

    公开(公告)号：US20190062370A1

    公开(公告)日：2019-02-28

    申请号：US16080453

    申请日：2017-03-01

    Applicant: Bayer CropScience LP

    Inventor： Chad KIMMELSHUE ,  Yan LI ,  Colleen S. TAYLOR ,  Hong ZHU

    IPC: C07K1/36 ,  C07K7/64 ,  C07K1/30 ,  C12P19/04

    Abstract: The present invention provides a method of enriching a lipopeptide in a microbial cell culture, the method comprising mixing an amphiphilic sulfonate and/or an amphiphilic sulfate with the cell culture to induce the formation of aggregates containing the lipopeptide, centrifuging the cell culture to generate a supernatant fraction and a pellet fraction, separating the pellet fraction from the supernatant fraction, and mixing the pellet fraction with a polyoxyethylene glycol alkyl ether to release the lipopeptide from the aggregates. Also provided is a method of purifying an exopolysaccharide from a microbial cell culture, the method comprising mixing an amphiphilic sulfonate and/or an amphiphilic sulfate with the cell culture to induce the formation of aggregates, centrifuging the cell culture to generate a supernatant fraction and a pellet fraction, separating the supernatant fraction from the pellet fraction, adding alcohol to the supernatant fraction to precipitate the exopolysaccharide; and removing the precipitated exopolysaccharide from the supernatant fraction.

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