公开(公告)号：US10414730B2

公开(公告)日：2019-09-17

申请号：US15969633

申请日：2018-05-02

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Wahed Ahmed Moradi ,  Thomas Himmler ,  Thomas Norbert Müller ,  Albert Schnatterer ,  Günter Schlegel

IPC: C07D213/56 ,  C07D213/89 ,  C07D213/38 ,  C07D213/57

Abstract: The present invention relates to a novel catalytic hydrogenation of substituted 2-methyl cyanopyridyl derivatives, in particular 3-chloro-5-(trifluoromethyl)pyridin-2-yl]acetonitrile [=Py-CN] to substituted 2-ethylaminopyridine derivatives, in particular 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethanamine [=Py-ethanamine] or salts thereof in the presence of metal catalysts, in particular palladium catalysts.

公开(公告)号：US20180244621A1

公开(公告)日：2018-08-30

申请号：US15969633

申请日：2018-05-02

Applicant: Bayer Cropscience Aktiengesellschaft

Inventor： Wahed Ahmed Moradi ,  Thomas Himmler ,  Thomas Norbert Müller ,  Albert Schnatterer ,  Günter Schlegel

IPC: C07D213/56 ,  C07D213/89 ,  C07D213/38 ,  C07D213/57

CPC classification number: C07D213/56 ,  C07D213/38 ,  C07D213/57 ,  C07D213/89

Abstract: The present invention relates to a novel catalytic hydrogenation of substituted 2-methyl cyanopyridyl derivatives, in particular 3-chloro-5-(trifluoromethyl)pyridin-2-yl]acetonitrile [=Py-CN] to substituted 2-ethylaminopyridine derivatives, in particular 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethanamine [=Py-ethanamine] or salts thereof in the presence of metal catalysts, in particular palladium catalysts.