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公开(公告)号:US10766859B2
公开(公告)日:2020-09-08
申请号:US16471144
申请日:2017-12-18
Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
Inventor: Wahed Ahmed Moradi , Thomas Himmler , Thomas Norbert Mueller
IPC: C07D213/26 , C07D213/40 , C07D213/60 , C07D213/61
Abstract: The present invention relates to a novel catalytic hydrogenation of substituted 2-methyl cyanopyridyl derivatives, in particular 3-chloro-5-(trifluoromethyl)pyridin-2-yl]acetonitrile [=Py-CN] to substituted 2-ethylaminopyridine derivatives, in particular 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethanamine [=Py-ethanamine] or salts thereof in the presence of Raney catalysts, in particular Raney nickel or cobalt.
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公开(公告)号:US10435352B2
公开(公告)日:2019-10-08
申请号:US15769765
申请日:2016-10-21
Applicant: Bayer CropScience Aktiengesellschaft
Inventor: Christian Funke , Thomas Himmler , Sergii Pazenok , Christoph Schotes , Matthias Beller , Thomas Schareina , Alexander Zapf
IPC: C07C253/14 , C07C255/50 , C07C315/02 , C07C319/14 , C07C319/20 , C07C323/62 , C07C25/13 , C07C323/36
Abstract: A process for preparing 2-alkyl-4-trifluoromethyl-3-alkylsulfonylbenzoic acids of the formula (I) is described. Here, the substituents are radicals such as alkyl and substituted phenyl.
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公开(公告)号:US10011557B2
公开(公告)日:2018-07-03
申请号:US15523038
申请日:2015-11-02
Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
Inventor: Thomas Himmler , Lars Rodefeld , Jonathan Hubrich , Lutz Ackermann
IPC: C07C209/42 , C07C213/02 , C07C227/04 , C07C211/45 , C07C229/52 , C07C245/08
CPC classification number: C07C209/42 , C07C211/45 , C07C213/02 , C07C221/00 , C07C227/04 , C07C229/52 , C07C245/08 , C07C211/52 , C07C217/80 , C07C225/22
Abstract: The present invention relates to a novel method for preparing substituted biphenylamines.
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公开(公告)号:US11220511B2
公开(公告)日:2022-01-11
申请号:US16322556
申请日:2017-07-31
Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
Inventor: Thomas Himmler , Julia Johanna Hahn , Joachim Crede
IPC: C07D491/113 , C07D319/08 , C07D407/12 , C07D317/72 , A01N43/90
Abstract: The invention relates to a novel process for preparing spiroketal-substituted cyclic ketoenols which can be used as insecticides, acaricides or herbicides. The present invention also relates to novel intermediates for the preparation of spiroketal-substituted cyclic ketoenols.
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公开(公告)号:US10519085B2
公开(公告)日:2019-12-31
申请号:US16070244
申请日:2017-01-09
Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
Inventor: Thomas Himmler , Peter Brüchner
Abstract: The invention relates to a process for preparing substituted 2-arylethanols of the formula (I) by reacting Grignard compounds of the formula (II) in the presence of a copper compound with ethylene oxide. Moreover, the invention relates to novel substituted 2-arylethanols of the formula (I).
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公开(公告)号:US10246408B2
公开(公告)日:2019-04-02
申请号:US16113624
申请日:2018-08-27
Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
Inventor: Thomas Himmler , Lars Rodefeld , Jonathan Hubrich , Lutz Ackermann
IPC: C07C231/12
Abstract: The present invention relates to a novel process for preparing substituted biphenylamides of the general formula (V) characterized in that anilides of the formula (II) in a solvent other than tetrahydrofuran, are reacted with an organoboron compound of the formula (III) in the presence of a catalyst system consisting of a ruthenium catalyst, an activator, an oxidizing agent and a metal triflate.
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公开(公告)号:US09988353B2
公开(公告)日:2018-06-05
申请号:US15033987
申请日:2014-11-11
Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
Inventor: Wahed Ahmed Moradi , Thomas Himmler , Thomas Norbert Mueller , Albert Schnatterer , Guenter Schlegel
IPC: C07D213/56 , C07D213/89 , C07D213/38 , C07D213/57
CPC classification number: C07D213/56 , C07D213/38 , C07D213/57 , C07D213/89
Abstract: The present invention relates to a novel catalytic hydrogenation of substituted 2-methyl cyanopyridyl derivatives, in particular 3-chloro-5-(trifluoromethyl)pyridin-2-yl]acetonitrile [=Py-CN] to substituted 2-ethylaminopyridine derivatives, in particular 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethanamine [=Py-ethanamine] or salts thereof in the presence of metal catalysts, in particular palladium catalysts.
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公开(公告)号:US10414730B2
公开(公告)日:2019-09-17
申请号:US15969633
申请日:2018-05-02
Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
Inventor: Wahed Ahmed Moradi , Thomas Himmler , Thomas Norbert Müller , Albert Schnatterer , Günter Schlegel
IPC: C07D213/56 , C07D213/89 , C07D213/38 , C07D213/57
Abstract: The present invention relates to a novel catalytic hydrogenation of substituted 2-methyl cyanopyridyl derivatives, in particular 3-chloro-5-(trifluoromethyl)pyridin-2-yl]acetonitrile [=Py-CN] to substituted 2-ethylaminopyridine derivatives, in particular 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethanamine [=Py-ethanamine] or salts thereof in the presence of metal catalysts, in particular palladium catalysts.
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公开(公告)号:US10246407B2
公开(公告)日:2019-04-02
申请号:US15305865
申请日:2015-04-22
Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
Inventor: Thomas Himmler , Lars Rodefeld , Jonathan Hubrich , Lutz Ackermann
IPC: C07C231/12
Abstract: The present invention relates to a novel process for preparing substituted biphenylamides of the general formula (V) characterized in that anilides of the formula (II) in a solvent other than tetrahydrofuran, are reacted with an organoboron compound of the formula (III) in the presence of a catalyst system consisting of a ruthenium catalyst, an activator, an oxidizing agent and a metal triflate.
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公开(公告)号:US10150731B2
公开(公告)日:2018-12-11
申请号:US15542715
申请日:2016-01-13
Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
Inventor: Thomas Himmler , Dirk Brohm
IPC: C07D211/62
Abstract: The present invention describes a novel method for preparing 4-cyanopiperidine hydrochloride.
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