公开(公告)号：US10662185B2

公开(公告)日：2020-05-26

申请号：US16025087

申请日：2018-07-02

申请人： BAYER PHARMA AKTIENGESELLSCHAFT

发明人： Alexandros Vakalopoulos ,  Markus Follman ,  Ingo Hartung ,  Philipp Buchgraber ,  Rolf Jautelat ,  Jorma Haßfeld ,  Niels Lindner ,  Alexey Gromov ,  Frank Wunder ,  Johannes-Peter Stasch ,  Gorden Redlich ,  Volkhart Min-Jian Li ,  Eva Maria Becker-Pelster ,  Andreas Knorr

IPC分类号： C07D471/04 ,  A61K31/437 ,  A61K31/439 ,  A61K31/4985 ,  A61K45/06 ,  C07D471/08 ,  A61K31/496 ,  A61K31/5377 ,  A61K31/541 ,  C07D519/00 ,  A61K31/444 ,  A61K31/4545 ,  A61K31/4709 ,  A61K31/55 ,  A61K31/4375 ,  A61K31/4725

摘要： The present application relates to novel substituted imidazo[1,2-a]pyridine-3-carboxamides of the general formula (I) to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.

公开(公告)号：US08796305B2

公开(公告)日：2014-08-05

申请号：US13789414

申请日：2013-03-07

申请人： Bayer Pharma Aktiengesellschaft

发明人： Alexandros Vakalopoulos ,  Ingo Hartung ,  Markus Follman ,  Rolf Jautelat ,  Niels Lindner ,  Dirk Schneider ,  Frank Wunder ,  Johannes-Peter Stasch ,  Gorden Redlich ,  Volkhart Min-Jian Li

IPC分类号： C07D401/10 ,  C07D401/02 ,  A61K31/4353

CPC分类号： C07D401/10 ,  A61K31/4353 ,  A61K31/437 ,  A61K45/06 ,  C07D401/02 ,  C07D471/04

摘要： The present application relates to novel substituted imidazo[1,2-a]pyridine-3-carboxamides, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.

摘要翻译： 本申请涉及新的取代的咪唑并[1,2-a]吡啶-3-甲酰胺，其制备方法单独使用或组合用于治疗和/或预防疾病及其用于制备药物的用途 用于治疗和/或预防疾病，特别是用于治疗和/或预防心血管疾病。