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公开(公告)号:US11344519B2
公开(公告)日:2022-05-31
申请号:US17132765
申请日:2020-12-23
发明人: Anke Stroyer , Carmen Lobback , Peter Serno , Philipp Rubenbauer , Kai Lovis , Heiko Schirmer , Danja Grossbach , Donald Bierer , Britta Olenik , Tia Jacobs , Julia Küsel
IPC分类号: A61K31/00 , A61K9/00 , A61K31/192 , A61K9/20 , A61K47/10 , A61K47/38 , A61K45/06 , A61P25/28 , A61P13/00 , A61P9/10
摘要: The present invention relates to orally administrable modified-release pharmaceutical dosage forms comprising sodium (3S)-3-(4-chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino}phenyl)-3-cyclopropylpropanoate and to processes for preparing the dosage forms and to their use for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiac, renal and pulmonary disorders, disorders of the central nervous system, fibrotic and inflammatory disorders and metabolic disorders.
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公开(公告)号:US10905667B2
公开(公告)日:2021-02-02
申请号:US16043567
申请日:2018-07-24
发明人: Anke Stroyer , Carmen Lobback , Peter Serno , Philipp Rubenbauer , Kai Lovis , Heiko Schirmer , Danja Grossbach , Donald Bierer , Britta Olenik , Tia Jacobs , Julia Küsel
IPC分类号: A61K31/00 , A61K9/00 , A61K47/00 , A61P9/10 , A61P25/28 , A61K31/192 , A61K9/20 , A61K47/10 , A61K47/38 , A61K45/06 , A61P13/00
摘要: The present invention relates to orally administrable modified-release pharmaceutical dosage forms comprising sodium (3S)-3-(4-chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino}phenyl)-3-cyclopropylpropanoate and to processes for preparing the dosage forms and to their use for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiac, renal and pulmonary disorders, disorders of the central nervous system, fibrotic and inflammatory disorders and metabolic disorders.
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公开(公告)号:US20200030270A1
公开(公告)日:2020-01-30
申请号:US16043567
申请日:2018-07-24
发明人: Anke Stroyer , Carmen Lobback , Peter Serno , Philipp Rubenbauer , Kai Lovis , Heiko Schirmer , Danja Grossbach , Donald Bierer , Britta Olenik , Tia Jacobs , Julia Kusel
摘要: The present invention relates to orally administrable modified-release pharmaceutical dosage forms comprising sodium (3S)-3-(4-chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino}phenyl)-3-cyclopropylpropanoate and to processes for preparing the dosage forms and to their use for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiac, renal and pulmonary disorders, disorders of the central nervous system, fibrotic and inflammatory disorders and metabolic disorders.
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公开(公告)号:US20220257547A1
公开(公告)日:2022-08-18
申请号:US17732761
申请日:2022-04-29
发明人: Anke Stroyer , Carmen Lobback , Peter Serno , Philipp Rubenbauer , Kai Lovis , Heiko Schirmer , Danja Grossbach , Donald Bierer , Britta Olenik , Tia Jacobs , Julia Küsel
摘要: The present invention relates to orally administrable modified-release pharmaceutical dosage forms comprising sodium (3S)-3-(4-chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino}phenyl)-3-cyclopropylpropanoate and to processes for preparing the dosage forms and to their use for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiac, renal and pulmonary disorders, disorders of the central nervous system, fibrotic and inflammatory disorders and metabolic disorders.
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公开(公告)号:US20210113504A1
公开(公告)日:2021-04-22
申请号:US17132765
申请日:2020-12-23
发明人: Anke Stroyer , Carmen Lobback , Peter Serno , Philipp Rubenbauer , Kai Lovis , Heiko Schirmer , Danja Grossbach , Donald Bierer , Britta Olenik , Tia Jacobs , Julia Küsel
摘要: The present invention relates to orally administrable modified-release pharmaceutical dosage forms comprising sodium (3S)-3-(4-chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino}phenyl)-3-cyclopropylpropanoate and to processes for preparing the dosage forms and to their use for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiac, renal and pulmonary disorders, disorders of the central nervous system, fibrotic and inflammatory disorders and metabolic disorders.
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