公开(公告)号：US20220274979A1

公开(公告)日：2022-09-01

申请号：US17048561

申请日：2019-04-15

申请人： Bayer Pharma Aktiengesellschaft ,  Bayer Healthcare China

发明人： Lars WORTMANN ,  Brice SAUTIER ,  Knut EIS ,  Hans BRIEM ,  Niels BÖHNKE ,  Franz VON NUSSBAUM ,  Roman HILIG ,  Benjamin BADER ,  Jens SCHRÖDER ,  Kirstin PETERSEN ,  Philip LIENAU ,  Antje Margret WENGNER ,  Dieter MOOSMAYER ,  Qiuwen WANG ,  Hans SCHICK

IPC分类号： C07D471/04 ,  C07D487/04

摘要： The present invention covers 2-methyl-aza-quinazoline compounds of general formula (I) as described and defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients