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公开(公告)号:US20170095573A1
公开(公告)日:2017-04-06
申请号:US15316040
申请日:2015-06-02
Applicant: Baylor Research Institute
Inventor: SangKon OH , Bob Kane , Gerard Zurawski
CPC classification number: A61K47/543 , A61K47/6803 , A61K47/6849 , A61K2039/505 , A61K2039/577 , C07K16/2851 , C07K2317/24 , C07K2317/33 , C07K2317/75 , C07K2317/76
Abstract: Described herein are therapeutic approaches with immune modifiers of the Th2 pathway for the treatment of allergic and inflammatory diseases. Aspects of the disclosure relate to methods for decreasing Th2-type cell responses in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an anti-Dectin-1 antibody or antigen binding fragment thereof operatively linked to a TLR agonist.