公开(公告)号：US06551607B1

公开(公告)日：2003-04-22

申请号：US09474490

申请日：1999-12-29

申请人： Bernard Joseph Minerath, III ,  David Roland Otts ,  Linda Susan Huard ,  David John Tyrrell ,  Robert Cosmo DiLuccio ,  Frank Jerrel Akin ,  Chantel Spring Buhrow ,  Dennis Stein Everhart ,  Brenda Marie Nelson ,  Gary Lee Shanklin

发明人： Bernard Joseph Minerath, III ,  David Roland Otts ,  Linda Susan Huard ,  David John Tyrrell ,  Robert Cosmo DiLuccio ,  Frank Jerrel Akin ,  Chantel Spring Buhrow ,  Dennis Stein Everhart ,  Brenda Marie Nelson ,  Gary Lee Shanklin

IPC分类号： A01N2534

CPC分类号： A61K8/19 ,  A61K8/02 ,  A61K8/0208 ,  A61K8/25 ,  A61K8/26 ,  A61K8/29 ,  A61K2800/75 ,  A61L15/18 ,  A61L15/34 ,  A61L15/46 ,  A61L2300/22 ,  A61L2300/412 ,  A61Q19/00 ,  A61Q19/10

摘要： The present invention relates to a method of sequestering skin irritants with a skin irritant sequestering composition comprising a substrate, a hydrophilic skin irritant sequestering agent and a hydrophobic skin irritant sequestering agent. In one embodiment the sequestering agents are comprised of modified and non-modified clays. The present invention further also provides a method of sequestering skin irritants comprising administering to the stratum corneum of an individual's skin a skin irritant sequestering composition comprising a substrate, a skin irritant sequestering amount of a combination of hydrophilic and hydrophobic skin irritant sequestering agents. In one embodiment the skin irritants are bound to sequestering agents present on a substrate. In another embodiment the skin irritants are bound to sequestering agents present on the skin.

摘要翻译： 本发明涉及一种用皮肤刺激性螯合组合物螯合皮肤刺激物的方法，其包含底物，亲水性皮肤刺激性螯合剂和疏水性皮肤刺激性螯合剂。 在一个实施方案中，螯合剂由改性和未改性的粘土组成。 本发明还提供了一种螯合皮肤刺激剂的方法，包括对个体皮肤的角质层施用皮肤刺激性螯合组合物，其包含底物，皮肤刺激物螯合量的亲水和疏水性皮肤刺激性螯合剂的组合。 在一个实施方案中，皮肤刺激物与存在于底物上的螯合剂结合。 在另一个实施方案中，皮肤刺激物与存在于皮肤上的螯合剂结合。

公开(公告)号：US06521241B1

公开(公告)日：2003-02-18

申请号：US09474307

申请日：1999-12-29

申请人： Bernard Joseph Minerath, III ,  David Roland Otts ,  Linda Susan Huard ,  David John Tyrrell ,  Robert Cosmo DiLuccio ,  Frank Jerrel Akin ,  Chantel Spring Buhrow ,  Dennis Stein Everhart ,  Brenda Marie Nelson ,  Gary Lee Shanklin

发明人： Bernard Joseph Minerath, III ,  David Roland Otts ,  Linda Susan Huard ,  David John Tyrrell ,  Robert Cosmo DiLuccio ,  Frank Jerrel Akin ,  Chantel Spring Buhrow ,  Dennis Stein Everhart ,  Brenda Marie Nelson ,  Gary Lee Shanklin

IPC分类号： A01N2534

CPC分类号： A61K8/19 ,  A61K8/02 ,  A61K8/0208 ,  A61K8/25 ,  A61K8/26 ,  A61K8/29 ,  A61K2800/75 ,  A61L15/18 ,  A61L15/34 ,  A61L15/46 ,  A61L2300/22 ,  A61L2300/412 ,  A61Q19/00 ,  A61Q19/10

摘要： The present invention relates to a skin irritant sequestering composition comprising a tissue substrate, a hydrophilic skin irritant sequestering agent and a hydrophobic skin irritant sequestering agent. In one embodiment the sequestering agents are comprised of modified and non-modified clays. In one embodiment, the skin irritants are bound to sequestering agents present on a substrate. In another embodiment the skin irritants are bound to sequestering agents present on the skin.

摘要翻译： 本发明涉及皮肤刺激性螯合组合物，其包含组织底物，亲水性皮肤刺激性螯合剂和疏水性皮肤刺激性螯合剂。 在一个实施方案中，螯合剂由改性和未改性的粘土组成。 在一个实施方案中，皮肤刺激物与存在于底物上的螯合剂结合。 在另一个实施方案中，皮肤刺激物与存在于皮肤上的螯合剂结合。

公开(公告)号：US06485733B1

公开(公告)日：2002-11-26

申请号：US09475535

申请日：1999-12-30

申请人： Linda Susan Huard ,  David John Tyrrell ,  David Roland Otts ,  Bernard Joseph Minerath, III ,  Brenda Marie Nelson ,  Chantel Spring Buhrow ,  Dennis Stein Everhart ,  Robert Cosmo DiLuccio ,  Frank Jerrel Akin

发明人： Linda Susan Huard ,  David John Tyrrell ,  David Roland Otts ,  Bernard Joseph Minerath, III ,  Brenda Marie Nelson ,  Chantel Spring Buhrow ,  Dennis Stein Everhart ,  Robert Cosmo DiLuccio ,  Frank Jerrel Akin

IPC分类号： A01N2534

CPC分类号： A61K8/19 ,  A61K8/02 ,  A61K8/0208 ,  A61K8/25 ,  A61K8/26 ,  A61K8/29 ,  A61K2800/75 ,  A61L15/18 ,  A61L15/34 ,  A61L15/46 ,  A61L2300/22 ,  A61L2300/412 ,  A61Q19/00 ,  A61Q19/10

摘要： Absorbent personal care articles, such a diapers and adult incontinent briefs, are provided comprising an absorbent article and having disposed thereon a skin irritant sequestering effective amount of an unmodified particulate skin irritant sequestering agent, and a lipophilic skin health benefit agent. An unmodified particulate skin irritant sequestering agent can be a clay, such as bentonite or laponite unmodified by organic amphiphilic compounds. A lipophilic skin health benefit agent can be stearic acid, isoparrafin, petrolatum, and a combination thereof. The skin irritant can be bound to the sequestering agent either on an individual's skin or on the absorbent article.

摘要翻译： 提供吸收性个人护理制品，例如尿布和成人失禁内裤，其包括吸收制品，并且在其上设置有皮肤刺激性螯合有效量的未改性颗粒皮肤刺激性螯合剂和亲脂性皮肤健康益处剂。 未改性的颗粒状皮肤刺激性螯合剂可以是未经有机两亲性化合物改性的粘土，例如膨润土或双螺旋体。 亲脂性皮肤健康有益剂可以是硬脂酸，异链球蛋白，凡士林及其组合。 皮肤刺激物可以在个人皮肤上或吸收制品上与螯合剂结合。

公开(公告)号：US06517848B1

公开(公告)日：2003-02-11

申请号：US09475825

申请日：1999-12-30

申请人： Linda Susan Huard ,  David John Tyrrell ,  David Roland Otts ,  Bernard Joseph Minerath, III ,  Brenda Marie Nelson ,  Chantel Spring Buhrow ,  Dennis Stein Everhart ,  Robert Cosmo DiLuccio ,  Frank Jerrel Akin

发明人： Linda Susan Huard ,  David John Tyrrell ,  David Roland Otts ,  Bernard Joseph Minerath, III ,  Brenda Marie Nelson ,  Chantel Spring Buhrow ,  Dennis Stein Everhart ,  Robert Cosmo DiLuccio ,  Frank Jerrel Akin

IPC分类号： A01N2534

CPC分类号： A61K8/19 ,  A61K8/02 ,  A61K8/0208 ,  A61K8/25 ,  A61K8/26 ,  A61K8/29 ,  A61K2800/75 ,  A61L15/18 ,  A61L15/34 ,  A61L15/46 ,  A61L2300/22 ,  A61L2300/412 ,  A61Q19/00 ,  A61Q19/10

摘要： Methods of using absorbent personal care articles, such a diapers and adult incontinent briefs, comprising an absorbent article and having disposed thereon a skin irritant sequestering effective amount of an unmodified particulate skin irritant sequestering agent, and a lipophilic skin health benefit agent are provided. An unmodified particulate skin irritant sequestering agent can be a clay, such as bentonite or laponite unmodified by organic amphiphilic compounds. A lipophilic skin health benefit agent can be stearic acid, isoparrafin, petrolatum, and a combination thereof. The skin irritant can be bound to the sequestering agent either on an individual's skin or on the absorbent article.

摘要翻译： 提供了使用吸收性个人护理用品，例如尿布和成人失禁内裤的方法，其包括吸收制品并且在其上设置有皮肤刺激性螯合有效量的未改性颗粒皮肤刺激性螯合剂和亲脂性皮肤健康益处剂。 未改性的颗粒状皮肤刺激性螯合剂可以是未经有机两亲性化合物改性的粘土，例如膨润土或双螺旋体。 亲脂性皮肤健康有益剂可以是硬脂酸，异链球蛋白，凡士林及其组合。 皮肤刺激物可以在个人皮肤上或吸收制品上与螯合剂结合。

公开(公告)号：US06521242B1

公开(公告)日：2003-02-18

申请号：US09474581

申请日：1999-12-29

申请人： Bernard Joseph Minerath, III ,  Brenda Marie Nelson ,  David Roland Otts ,  Linda Susan Huard ,  David John Tyrrell ,  Gary Lee Shanklin

发明人： Bernard Joseph Minerath, III ,  Brenda Marie Nelson ,  David Roland Otts ,  Linda Susan Huard ,  David John Tyrrell ,  Gary Lee Shanklin

IPC分类号： A01N2534

CPC分类号： A61K8/19 ,  A61K8/02 ,  A61K8/0208 ,  A61K8/25 ,  A61K8/26 ,  A61K8/29 ,  A61K2800/75 ,  A61L15/18 ,  A61L15/34 ,  A61L15/46 ,  A61L2300/22 ,  A61L2300/412 ,  A61Q19/00 ,  A61Q19/10

摘要： The present invention provides a method of sequestering nasal secretion skin irritants comprising administering to the stratum corneum of an individual's skin a facial tissue comprising a tissue substrate, a nasal secretion skin irritant sequestering amount of a combination of hydrophilic and hydrophobic nasal secretion skin irritant sequestering agents. In one embodiment the sequestering agents are comprised of modified and non-modified clays. In one embodiment the skin irritants are bound to sequestering agents present on a substrate. In another embodiment the skin irritants are bound to sequestering agents present on the skin.

摘要翻译： 本发明提供了一种隔离鼻分泌皮肤刺激物的方法，其包括对个体皮肤的角质层施用包含组织底物的面部组织，鼻分泌皮肤刺激性螯合量的亲水和疏水性鼻分泌皮肤刺激性螯合剂的组合 。 在一个实施方案中，螯合剂由改性和未改性的粘土组成。 在一个实施方案中，皮肤刺激物与存在于底物上的螯合剂结合。 在另一个实施方案中，皮肤刺激物与存在于皮肤上的螯合剂结合。

公开(公告)号：US06521240B1

公开(公告)日：2003-02-18

申请号：US09473675

申请日：1999-12-29

申请人： Bernard Joseph Minerath, III ,  Brenda Marie Nelson ,  David Roland Otts ,  Linda Susan Huard ,  David John Tyrrell ,  Gary Lee Shanklin

发明人： Bernard Joseph Minerath, III ,  Brenda Marie Nelson ,  David Roland Otts ,  Linda Susan Huard ,  David John Tyrrell ,  Gary Lee Shanklin

IPC分类号： A01N2534

CPC分类号： A61K8/19 ,  A61K8/02 ,  A61K8/0208 ,  A61K8/25 ,  A61K8/26 ,  A61K8/29 ,  A61K2800/75 ,  A61L15/18 ,  A61L15/34 ,  A61L15/46 ,  A61L2300/22 ,  A61L2300/412 ,  A61Q19/00 ,  A61Q19/10

摘要： Facial tissue is provided comprising a tissue substrate, a hydrophilic nasal secretion skin irritant sequestering agent and a hydrophobic nasal secretion skin irritant sequestering agent. In one embodiment the sequestering agents are comprised of modified and non-modified clays. In one embodiment the skin irritants are bound to sequestering agents present on a substrate. In another embodiment the skin irritants are bound to sequestering agents present on the skin.

摘要翻译： 提供包括组织底物，亲水性鼻分泌皮肤刺激性螯合剂和疏水性鼻分泌皮肤刺激性螯合剂的面部组织。 在一个实施方案中，螯合剂由改性和未改性的粘土组成。 在一个实施方案中，皮肤刺激物与存在于底物上的螯合剂结合。 在另一个实施方案中，皮肤刺激物与存在于皮肤上的螯合剂结合。

公开(公告)号：US06500443B1

公开(公告)日：2002-12-31

申请号：US09578761

申请日：2000-05-25

申请人： David Roland Otts ,  David John Tyrrell ,  Linda Susan Huard ,  Frank Jerrel Akin ,  Robert Cosmo Di Luccio

发明人： David Roland Otts ,  David John Tyrrell ,  Linda Susan Huard ,  Frank Jerrel Akin ,  Robert Cosmo Di Luccio

IPC分类号： A61N2534

CPC分类号： A61Q19/00 ,  A61K8/0208 ,  A61K9/70 ,  A61K2800/782 ,  A61L15/225 ,  C08L89/00

摘要： The present invention relates to a topical delivery system effective in depositing a thin, tenacious and substantially continuous coating of a sacrificial substrate on skin by an aqueous emulsion mediated dissolution of protein from a sheet material with subsequent transfer and deposition onto the skin. Coatings of sacrificial substrate on skin resist removal, thereby providing a protective barrier against chemically- and biochemically-induced skin damage. The treatment composition also provides a vehicle for administering an effective dose of an active agent to the skin surface.

摘要翻译： 本发明涉及一种局部递送系统，其有效地通过水性乳剂介导的蛋白质从片材的溶解而沉积在皮肤上的薄而牢固且基本上连续的牺牲基质涂层，随后转移和沉积到皮肤上。 牺牲基材在皮肤上的涂层抵抗去除，从而提供防止化学和生物化学诱导的皮肤损伤的保护屏障。 治疗组合物还提供了向皮肤表面施用有效剂量的活性剂的载体。

公开(公告)号：US06503525B1

公开(公告)日：2003-01-07

申请号：US09671357

申请日：2000-09-27

申请人： Susan Carol Paul ,  Frank Jerrel Akin ,  Robert Cosmo Di Luccio ,  Dennis Stein Everhart ,  Elizabeth Deibler Gadsby ,  Pamela Jean Mayberry ,  Audra Stefanik Wright ,  Ali Yahiaoui ,  Michael John Faulks ,  Duane Gerard Krzysik ,  Karen Marie Menard ,  David Charles Musil ,  Frank Andrew Rosch, III ,  Gordon Allen Shaw ,  David John Tyrrell ,  Diane Michele Underhill ,  Jeffrey Michael Hockersmith ,  Gunilla Elsa Gillberg-LaForce ,  Wade Bolton May

发明人： Susan Carol Paul ,  Frank Jerrel Akin ,  Robert Cosmo Di Luccio ,  Dennis Stein Everhart ,  Elizabeth Deibler Gadsby ,  Pamela Jean Mayberry ,  Audra Stefanik Wright ,  Ali Yahiaoui ,  Michael John Faulks ,  Duane Gerard Krzysik ,  Karen Marie Menard ,  David Charles Musil ,  Frank Andrew Rosch, III ,  Gordon Allen Shaw ,  David John Tyrrell ,  Diane Michele Underhill ,  Jeffrey Michael Hockersmith ,  Gunilla Elsa Gillberg-LaForce ,  Wade Bolton May

IPC分类号： A01N2534

CPC分类号： A61L15/34 ,  A61F13/15203 ,  A61L15/46 ,  A61L2300/102 ,  A61L2300/252 ,  A61L2300/412

摘要： An absorbent article includes a vapor permeable backsheet, a liquid permeable topsheet positioned in facing relation with the backsheet; and an absorbent body located between the backsheet and the topsheet. The absorbent body may include multiple zones of high air permeability. The absorbent article may also include a ventilation layer between the absorbent body and the backsheet and a surge management layer between the absorbent body and the topsheet. The article exhibits improved air exchange within the article during use. As a result, the article maintains the temperature and exhibits substantially reduced levels of hydration of the wearer's skin when in use which renders the skin less susceptible to the viability of microorganisms. The absorbent article may further include lotion formulations and/or treatment compositions thereon for maintaining or improving skin health.

公开(公告)号：US06482422B1

公开(公告)日：2002-11-19

申请号：US09671356

申请日：2000-09-27

申请人： Susan Carol Paul ,  Frank Jerrel Akin ,  Robert Cosmo Di Luccio ,  Dennis Stein Everhart ,  Elizabeth Deibler Gadsby ,  Pamela Jean Mayberry ,  Audra Stefanik Wright ,  Ali Yahiaoui ,  Michael John Faulks ,  Duane Gerard Krzysik ,  Karen Marie Menard ,  David Charles Musil ,  Frank Andrew Rosch, III ,  Gordon Allen Shaw ,  David John Tyrrell ,  Diane Michele Underhill ,  Jeffrey Michael Hockersmith ,  Gunilla Elsa Gillberg-LaForce ,  Wade Bolton May

发明人： Susan Carol Paul ,  Frank Jerrel Akin ,  Robert Cosmo Di Luccio ,  Dennis Stein Everhart ,  Elizabeth Deibler Gadsby ,  Pamela Jean Mayberry ,  Audra Stefanik Wright ,  Ali Yahiaoui ,  Michael John Faulks ,  Duane Gerard Krzysik ,  Karen Marie Menard ,  David Charles Musil ,  Frank Andrew Rosch, III ,  Gordon Allen Shaw ,  David John Tyrrell ,  Diane Michele Underhill ,  Jeffrey Michael Hockersmith ,  Gunilla Elsa Gillberg-LaForce ,  Wade Bolton May

IPC分类号： A01N2534

CPC分类号： A61L15/34 ,  A61F13/15203 ,  A61L15/46 ,  A61L2300/102 ,  A61L2300/252 ,  A61L2300/412

摘要： An absorbent article includes a vapor permeable backsheet, a liquid permeable topsheet positioned in facing relation with the backsheet; and an absorbent body located between the backsheet and the topsheet. The absorbent body may include multiple zones of high air permeability. The absorbent article may also include a ventilation layer between the absorbent body and the backsheet and a surge management layer between the absorbent body and the topsheet. The article exhibits improved air exchange within the article during use. As a result, the article maintains the temperature and exhibits substantially reduced levels of hydration of the wearer's skin when in use which renders the skin less susceptible to the viability of microorganisms. The absorbent article may further include lotion formulations and/or treatment compositions thereon for maintaining or improving skin health.

摘要翻译： 吸收性物品包括透气性底片，与底片相对定位的液体渗透性顶片; 以及位于底片和顶片之间的吸收体。 吸收体可以包括多个透气性高的区域。 吸收制品还可以包括在吸收体和底片之间的通气层和吸收体和顶片之间的浪涌管理层。 该文章在使用期间展示了在物品内的改进的空气交换。 结果，在使用时，制品保持温度并且在使用中显示出显着降低穿着者皮肤的水合水平，这使得皮肤对微生物的活力较不敏感。 吸收制品还可包括其上用于维持或改善皮肤健康的洗剂配方和/或治疗组合物。

公开(公告)号：US06296862B1

公开(公告)日：2001-10-02

申请号：US09671447

申请日：2000-09-27

申请人： Susan Carol Paul ,  Frank Jerrel Akin ,  Robert Cosmo Di Luccio ,  Dennis Stein Everhart ,  Elizabeth Deibler Gadsby ,  Pamela Jean Mayberry ,  Audra Stefanik Wright ,  Ali Yahiaoui ,  Michael John Faulks ,  Duane Gerard Krzysik ,  Karen Marie Menard ,  David Charles Musil ,  Frank Andrew Rosch, III ,  Gordon Allen Shaw ,  David John Tyrrell ,  Diane Michele Underhill ,  Jeffrey Michael Hockersmith ,  Gunilla Elsa Gillberg-LaForce ,  Wade Bolton May

发明人： Susan Carol Paul ,  Frank Jerrel Akin ,  Robert Cosmo Di Luccio ,  Dennis Stein Everhart ,  Elizabeth Deibler Gadsby ,  Pamela Jean Mayberry ,  Audra Stefanik Wright ,  Ali Yahiaoui ,  Michael John Faulks ,  Duane Gerard Krzysik ,  Karen Marie Menard ,  David Charles Musil ,  Frank Andrew Rosch, III ,  Gordon Allen Shaw ,  David John Tyrrell ,  Diane Michele Underhill ,  Jeffrey Michael Hockersmith ,  Gunilla Elsa Gillberg-LaForce ,  Wade Bolton May

IPC分类号： A61F1315

CPC分类号： A61L15/34 ,  A61F13/15203 ,  A61L15/46 ,  A61L2300/102 ,  A61L2300/252 ,  A61L2300/412

摘要： An absorbent article includes a vapor permeable backsheet, a liquid permeable topsheet positioned in facing relation with the backsheet; and an absorbent body located between the backsheet and the topsheet. The absorbent body may include multiple zones of high air permeability. The absorbent article may also include a ventilation layer between the absorbent body and the backsheet and a surge management layer between the absorbent body and the topsheet. The article exhibits improved air exchange within the article during use. As a result, the article maintains the temperature and exhibits substantially reduced levels of hydration of the wearer's skin when in use which renders the skin less susceptible to the viability of microorganisms. The absorbent article may further include lotion formulations and/or treatment compositions thereon for maintaining or improving skin health.

摘要翻译： 吸收性物品包括透气性底片，与底片相对定位的液体渗透性顶片; 以及位于底片和顶片之间的吸收体。 吸收体可以包括多个透气性高的区域。 吸收性物品还可以包括吸收体和底片之间的通气层和吸收体与顶片之间的浪涌管理层。 该文章在使用期间展示了在物品内的改进的空气交换。 结果，在使用时，制品保持温度并且在使用中显示出显着降低穿着者皮肤的水合水平，这使得皮肤对微生物的活力较不敏感。 吸收制品还可包括其上用于维持或改善皮肤健康的洗剂配方和/或治疗组合物。