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公开(公告)号:US20050143375A1
公开(公告)日:2005-06-30
申请号:US11020451
申请日:2004-12-22
申请人: Bernd Buettelmann , Simona Ceccarelli , Georg Jaeschke , Sabine Kolczewski , Richard Philip Porter , Eric Vieira , Anthony Ford , Yu Zhong
发明人: Bernd Buettelmann , Simona Ceccarelli , Georg Jaeschke , Sabine Kolczewski , Richard Philip Porter , Eric Vieira , Anthony Ford , Yu Zhong
IPC分类号: C07D401/06 , C07D401/14 , A61K31/541 , A61K31/4439 , A61K31/4545 , A61K31/496 , A61K31/5377
CPC分类号: C07D401/06 , C07D401/14
摘要: The present invention relates to imidazole derivatives of formula I wherein R1, R2, R3 and R4 are described hereinabove. These compounds can be used in the treatment or prevention of mGluR5 receptor mediated disorders. These compounds are useful, inter alia, in the treatment of genitourinary diseases.
摘要翻译: 本发明涉及式I的咪唑衍生物,其中R 1,R 2,R 3和R 4, 如上所述。 这些化合物可用于治疗或预防mGluR5受体介导的疾病。 这些化合物尤其用于治疗泌尿生殖系疾病。