Method for bacteriophage delivery and amplification
    1.
    发明申请
    Method for bacteriophage delivery and amplification 有权
    噬菌体递送和扩增方法

    公开(公告)号:US20070154459A1

    公开(公告)日:2007-07-05

    申请号:US11473449

    申请日:2006-06-23

    IPC分类号: A61K35/76 C12Q1/70

    CPC分类号: A61K35/76 C12N2795/10232

    摘要: Disclosed are methods of selecting wide host range bacteriophage capable of growing in a plurality of bacteria including pathogenic and non-pathogenic bacteria and bacteriophage selected by the methods. Also disclosed are methods of treating a subject infected with a pathogenic bacterium using bacteriophage and methods of decontaminating objects using bacteriophage. Also disclosed are methods of producing vaccines. In another aspect, methods of determining bacterial viability and methods of improving the sensitivity of a biosensor using wide host range bacteriophages are disclosed.

    摘要翻译: 公开了选择能够生长在多种细菌中的广泛宿主范围噬菌体的方法,所述多种细菌包括通过该方法选择的病原性和非致病性细菌和噬菌体。 还公开了使用噬菌体治疗感染病原菌的受试者的方法和使用噬菌体对物体去污的方法。 还公开了生产疫苗的方法。 在另一方面,公开了确定细菌存活力的方法和提高使用广泛的宿主范围噬菌体的生物传感器的灵敏度的方法。