公开(公告)号：US20230251255A1

公开(公告)日：2023-08-10

申请号：US18123777

申请日：2023-03-20

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Boaz GILDOR ,  Dalia SHEZIFI

IPC: G01N33/543 ,  G01N33/541

CPC classification number: G01N33/54386 ,  G01N33/541 ,  G01N33/54306

Abstract: Methods of detecting a target in a sample are provided. Kits for performing the methods described herein are also provided.

公开(公告)号：US20230340627A1

公开(公告)日：2023-10-26

申请号：US18296357

申请日：2023-04-05

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Polina TSIGANKOV ,  Dalia SHEZIFI ,  Galina FIHMAN ,  Matt DUNN ,  Brigid CUNNION

IPC: C12Q1/70 ,  G01N33/569

CPC classification number: C12Q1/701 ,  G01N33/56983 ,  C12Q1/6851

Abstract: Methods, compositions, and kits for analyzing viral particles. In an exemplary method of analyzing viral particles, capsids of the viral particles may be tagged with a tag. Subsamples of a sample containing the viral particles may be formed. Each subsample of only a subset of the subsamples may include at least one of the viral particles. One or more targets may be amplified from a genome of the viral particles. Tag-related data, and amplification data for the one or more targets, may be collected from the subsamples. In some examples, a capsid occupancy of the viral particles may be determined in a calibration-free approach using the collected data without quantification of the viral particles or capsids thereof.

公开(公告)号：US20170342463A1

公开(公告)日：2017-11-30

申请号：US15602667

申请日：2017-05-23

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Vered BRONNER ,  Dalia SHEZIFI

IPC: C12Q1/68

CPC classification number: C12Q1/6804 ,  C12Q1/6818 ,  C12Q1/6834 ,  C12Q2522/10 ,  C12Q2563/131

Abstract: Methods of determining the presence or absence of a target in a sample are provided. Kits for performing the methods described herein are also provided.