公开(公告)号：US20030113801A1

公开(公告)日：2003-06-19

申请号：US10263436

申请日：2002-10-01

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Steven R. Binder ,  Jodi L. Goodrich ,  Zara Safarian

IPC: G01N033/53

CPC classification number: G01N33/96 ,  G01N2333/9108 ,  Y10S435/973

Abstract: Analyses of serum samples for the presence and amount of either of the two subunits of human Factor XIII protein are used as a means of eliminating a significant source of error that arises in the testing of serum and plasma. For serum samples, a negative result of an analysis for the presence of subunit a is a means of verifying that a sample is indeed serum, while a negative or positive result for subunit a serves to distinguish serum (negative) from plasma (positive). A positive result for the presence of subunit b is a means of verifying that the sample is either serum or plasma and not any other biological fluid. A quantitative analysis of subunit b is a means of verifying that the sample is of the intended volume rather than having been reduced in volume due to improper sampling. A quantitative analysis of subunit b is also a means of verifying the dilution of a sample of either serum or plasma.