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公开(公告)号:US09752177B2
公开(公告)日:2017-09-05
申请号:US14256861
申请日:2014-04-18
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Yanhong Kong , Steven T. Okino , Xiangdong Meng
IPC: C12Q1/68
CPC classification number: C12Q1/6806 , C12Q2521/125 , C12Q2521/301 , C12Q2527/156
Abstract: Filtering small nucleic acids using permeabilized cells and methods for using the filtering to detect genomic DNA accessibility are described.
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公开(公告)号:US10683551B2
公开(公告)日:2020-06-16
申请号:US15411855
申请日:2017-01-20
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Steven T. Okino , Yan Wang
IPC: C12Q1/68 , C12Q1/6886 , C12Q1/6806 , C12Q1/6809 , C12Q1/6804
Abstract: This invention provides methods of determining the biological, pathological, genetic, epigenetic or disease status in a biological sample by determining the methylation status of a subpopulation of genomic DNA in the sample.
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公开(公告)号:US20160208312A9
公开(公告)日:2016-07-21
申请号:US14256861
申请日:2014-04-18
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Yanhong Kong , Steven T. Okino , Xiangdong Meng
IPC: C12Q1/68
CPC classification number: C12Q1/6806 , C12Q2521/125 , C12Q2521/301 , C12Q2527/156
Abstract: Filtering small nucleic acids using permeabilized cells and methods for using the filtering to detect genomic DNA accessibility are described.
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4.
公开(公告)号:US20140220586A1
公开(公告)日:2014-08-07
申请号:US14256861
申请日:2014-04-18
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Yanhong Kong , Steven T. Okino , Xiangdong Meng
IPC: C12Q1/68
CPC classification number: C12Q1/6806 , C12Q2521/125 , C12Q2521/301 , C12Q2527/156
Abstract: Filtering small nucleic acids using permeabilized cells and methods for using the filtering to detect genomic DNA accessibility are described.
Abstract translation: 描述使用透化细胞过滤小核酸和使用过滤检测基因组DNA可及性的方法。
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