公开(公告)号：US09752177B2

公开(公告)日：2017-09-05

申请号：US14256861

申请日：2014-04-18

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Yanhong Kong ,  Steven T. Okino ,  Xiangdong Meng

IPC: C12Q1/68

CPC classification number: C12Q1/6806 ,  C12Q2521/125 ,  C12Q2521/301 ,  C12Q2527/156

Abstract: Filtering small nucleic acids using permeabilized cells and methods for using the filtering to detect genomic DNA accessibility are described.

公开(公告)号：US10683551B2

公开(公告)日：2020-06-16

申请号：US15411855

申请日：2017-01-20

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Steven T. Okino ,  Yan Wang

IPC: C12Q1/68 ,  C12Q1/6886 ,  C12Q1/6806 ,  C12Q1/6809 ,  C12Q1/6804

Abstract: This invention provides methods of determining the biological, pathological, genetic, epigenetic or disease status in a biological sample by determining the methylation status of a subpopulation of genomic DNA in the sample.

公开(公告)号：US20160208312A9

公开(公告)日：2016-07-21

申请号：US14256861

申请日：2014-04-18

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Yanhong Kong ,  Steven T. Okino ,  Xiangdong Meng

IPC: C12Q1/68

CPC classification number: C12Q1/6806 ,  C12Q2521/125 ,  C12Q2521/301 ,  C12Q2527/156

Abstract: Filtering small nucleic acids using permeabilized cells and methods for using the filtering to detect genomic DNA accessibility are described.

公开(公告)号：US20140220586A1

公开(公告)日：2014-08-07

申请号：US14256861

申请日：2014-04-18

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Yanhong Kong ,  Steven T. Okino ,  Xiangdong Meng

IPC: C12Q1/68

CPC classification number: C12Q1/6806 ,  C12Q2521/125 ,  C12Q2521/301 ,  C12Q2527/156

Abstract: Filtering small nucleic acids using permeabilized cells and methods for using the filtering to detect genomic DNA accessibility are described.

Abstract translation: 描述使用透化细胞过滤小核酸和使用过滤检测基因组DNA可及性的方法。