公开(公告)号：US20240124849A1

公开(公告)日：2024-04-18

申请号：US18273430

申请日：2022-01-27

Applicant: BioMarin Pharmaceutical Inc.

Inventor： Vishal AGRAWAL ,  Teresa CHRISTIANSON ,  Francisco Javier FEMENIA ,  Santosh G. PANDE

IPC: C12N7/00 ,  C07K14/015 ,  C12N15/86

CPC classification number: C12N7/00 ,  C07K14/015 ,  C12N15/86 ,  C12N2750/14151

Abstract: The present invention provides modified alphaviruses and compositions, methods, and kits for preparing and using, in particular AAV viral particles pseudotyped with capsids, in particular for use in gene therapy and/or diagnostics.