公开(公告)号：US20150344550A1

公开(公告)日：2015-12-03

申请号：US14589372

申请日：2015-01-05

Applicant: Biogen Idec MA Inc.

Inventor： Anthony Rossomando ,  Ping Jin

IPC: C07K16/18 ,  G01N33/68

CPC classification number: C07K16/18 ,  C07K16/22 ,  C07K2317/21 ,  C07K2317/24 ,  C07K2317/54 ,  C07K2317/55 ,  C07K2317/622 ,  C07K2317/76 ,  G01N33/6827

Abstract: Antibodies and antigen binding fragments that bind to neublastin polypeptides are disclosed. Also disclosed are methods of using the antibodies and antigen binding fragments in assays for detecting the presence or amount of endogenous and/or exogenous neublastin in a sample and in methods of antagonizing neublastin bioactivity.

Abstract translation: 公开了结合新斯普霉素多肽的抗体和抗原结合片段。 还公开了在测定中使用抗体和抗原结合片段以检测样品中内源和/或外源性新生素的存在或量以及拮抗新兴霉素生物活性的方法中的方法。