公开(公告)号：US20170362324A1

公开(公告)日：2017-12-21

申请号：US15510422

申请日：2015-09-11

Applicant: Biogen MA Inc.

Inventor： Thomas Owen Cameron ,  Michael Adam Crackower ,  Brian M. Dolinski ,  Karl J.M. Hanf ,  Amy Theresa McCurley ,  Nels Eric Pederson ,  Martin Preyer ,  Fang Qian ,  Shelia M. Violette ,  Paul Henry Weinreb

IPC: C07K16/28

CPC classification number: C07K16/2839 ,  C07K2317/24 ,  C07K2317/41 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2317/94

Abstract: Humanized antibodies and antibody fragments that bind to αvβ5 are disclosed. Also disclosed are methods of using the disclosed antibodies and antibody fragments to treat or prevent αvβ5-mediated diseases.