公开(公告)号：US20230190719A1

公开(公告)日：2023-06-22

申请号：US17923585

申请日：2021-06-23

申请人： Biohaven Therapeutics Ltd.

发明人： Robert BERMAN ,  Rajesh KUMAR ,  Charles M. CONWAY ,  Mary K. DONOHUE ,  Ajaya Kumar REKA

IPC分类号： A61K31/4402 ,  A61K9/00 ,  A61K45/06 ,  A61K47/44

CPC分类号： A61K31/4402 ,  A61K9/0014 ,  A61K45/06 ,  A61K47/44

摘要： Provided is a pharmaceutical formulation including (1S)-1-phenyl-2-pyridin-2-ylethanamine, a pharmaceutically acceptable salt thereof, a solvate thereof, or a prodrug thereof; and a pharmaceutically acceptable topical carrier. Also provided is a method for treating neuropathic pain by administering to a patient in need of such treatment a therapeutically effective amount of the pharmaceutical formulation.

公开(公告)号：US20230181541A1

公开(公告)日：2023-06-15

申请号：US17923587

申请日：2021-06-24

申请人： Biohaven Therapeutics Ltd.

发明人： Vladimir CORIC ,  Robert BERMAN ,  Loren AGUIAR

IPC分类号： A61K31/428 ,  A61P25/18

CPC分类号： A61K31/428 ,  A61P25/18

摘要： Disclosed herein is a method for treating obsessive-compulsive disorder in a patient in need thereof by administering to the patient a dosage form including an effective amount of troriluzole.

公开(公告)号：US20240082340A1

公开(公告)日：2024-03-14

申请号：US18261419

申请日：2022-01-17

申请人： Biohaven Therapeutics Ltd.

发明人： Vladimir CORIC ,  Robert BERMAN

IPC分类号： A61K38/06 ,  A61K9/48 ,  A61P25/28

CPC分类号： A61K38/06 ,  A61K9/485 ,  A61K9/4858 ,  A61K9/4866 ,  A61P25/28

摘要： Disclosed are methods of treating a patient afflicted with Alzheimer's Disease of mild-to-moderate severity by administering to the patient a riluzole prodrug. Pharmaceutical compositions and kits including the riluzole prodrugs are also disclosed.

公开(公告)号：US20230390252A1

公开(公告)日：2023-12-07

申请号：US18353840

申请日：2023-07-17

申请人： Biohaven Therapeutics Ltd.

发明人： Vladimir CORIC ,  Robert BERMAN ,  Melissa BEINER ,  Gilbert L'Italien

IPC分类号： A61K31/428 ,  A61P25/00

CPC分类号： A61K31/428 ,  A61P25/00 ,  A61K9/20

摘要： Disclosed are methods of treating ataxia by administering to a patient in need thereof a riluzole prodrug such as troriluzole. Pharmaceutical compositions and kits including the riluzole prodrugs are also disclosed.

公开(公告)号：US20230355592A1

公开(公告)日：2023-11-09

申请号：US18353850

申请日：2023-07-17

申请人： Biohaven Therapeutics Ltd.

发明人： Vladimir CORIC ,  Robert BERMAN ,  Melissa BEINER ,  Gilbert L'Italien

IPC分类号： A61K31/428 ,  A61P25/00

CPC分类号： A61K31/428 ,  A61P25/00 ,  A61K9/20

摘要： Disclosed are methods of treating ataxia by administering to a patient in need thereof a riluzole prodrug such as troriluzole. Pharmaceutical compositions and kits including the riluzole prodrugs are also disclosed.