专利检索 ap:("Biosynth AG") AND inv:"Urs SPITZ" 第 1 页

1.

发明公开
POLYMORPHS OF 5-BROMO-6-CHLORO-3-INDOXYL CAPRYLATE 审中-公开

公开(公告)号：US20230348385A1

公开(公告)日：2023-11-02

申请号：US18041682

申请日：2021-08-17

申请人： Biosynth AG

发明人： Rith CHEAV , Urs SPITZ , Christophe E.M. WEYMUTH

IPC分类号： C07D209/36

CPC分类号： C07D209/36 , C07B2200/13

摘要： Polymorphs of 5-bromo-6-chloro-3-indoxyl caprylate characterized by the powder diffraction patterns as defined in FIG. 1 and FIG. 2.

2.

发明申请
METHOD OF MAKING NICOTINAMIDE RIBOFURANOSIDE SALTS, NICOTINAMIDE RIBOFURANOSIDE SALTS AS SUCH, AND USES THEREOF 有权

公开(公告)号：US20220251133A1

公开(公告)日：2022-08-11

申请号：US17711799

申请日：2022-04-01

申请人： Biosynth AG

发明人： Günter SCHABERT , Urs SPITZ , Aysel SOYDEMIR , Iris ZIMMERMANN

IPC分类号： C07H19/048 , C07H1/06

摘要： The present invention relates to a method of making nicotinamide ribofuranosie salts, in particular pharmaceutically acceptable nicotinamide ribofuranoside salts. The invention further relates to the nicotinamide ribofuranoside salts as such, in particular carboxylic acid salts in crystalline form, and their use in nutritional supplements and pharmaceutical compositions.

3.

发明申请
LUCIFERASE-BASED METHODS FOR DETECTING BACTERIAL AND FUNGAL CELLS AND ASSESSING SUSCEPTIBILITY OF BACTERIAL CELLS TO ANTIBIOTICS 有权

公开(公告)号：US20230110491A1

公开(公告)日：2023-04-13

申请号：US17908886

申请日：2021-03-08

申请人： Biosynth AG

发明人： Julian IHSSEN , Urs SPITZ

IPC分类号： C12Q1/20 , C12M1/32 , C12Q1/66

摘要： The present invention relates to a method for assessing cell viability of bacterial and fungal cells and to a method for the detection of bacterial and fungal cells with specific enzyme activities. The methods of the present invention rely on the real-time measurement of the level of luminescence signal from a luciferase enzyme directly from a growing culture of bacterial or fungal cells. Furthermore, the present invention relates to a method for assessing susceptibility of bacterial cells to antibiotics by measuring ATP levels using a luciferase assay system.

4.

发明申请
METHOD OF MAKING NICOTINAMIDE RIBOFURANOSIDE SALTS, NICOTINAMIDE RIBOFURANOSIDE SALTS AS SUCH, AND USES THEREOF 有权

公开(公告)号：US20220135610A1

公开(公告)日：2022-05-05

申请号：US17576699

申请日：2022-01-14

申请人： Biosynth AG

发明人： Günter SCHABERT , Urs SPITZ , Aysel SOYDEMIR , Iris ZIMMERMANN

IPC分类号： C07H19/048 , C07H1/06

摘要： The present invention relates to a method of making nicotinamide ribofuranoside salts, in particular pharmaceutically acceptable nicotinamide ribofuranoside salts. The invention further relates to the nicotinamide ribofuranoside salts as such, in particular carboxylic acid salts in crystalline form, and their use in nutritional supplements and pharmaceutical compositions.