公开(公告)号：US11225650B2

公开(公告)日：2022-01-18

申请号：US15619196

申请日：2017-06-09

Applicant: Bioverativ Therapeutics Inc.

Inventor： Glenn Pierce ,  Samantha Truex ,  Robert T. Peters ,  Haiyan Jiang ,  Mark Brader

IPC: A61K38/36 ,  C12N9/64 ,  C07K14/745 ,  C07K16/36 ,  A61K38/00

Abstract: The present invention provides methods of administering long-acting Factor IX; methods of administering long-acting, chimeric and hybrid polypeptides comprising Factor IX; and methods of producing such chimeric and hybrid polypeptides using cells.

公开(公告)号：US11193116B2

公开(公告)日：2021-12-07

申请号：US15619196

申请日：2017-06-09

Applicant: Bioverativ Therapeutics Inc.

Inventor： Glenn Pierce ,  Samantha Truex ,  Robert T. Peters ,  Haiyan Jiang ,  Mark Brader

IPC: A61K38/36 ,  C12N9/64 ,  C07K14/745 ,  C07K16/36 ,  A61K38/00

Abstract: The present invention provides methods of administering long-acting Factor IX; methods of administering long-acting, chimeric and hybrid polypeptides comprising Factor IX; and methods of producing such chimeric and hybrid polypeptides using cells.

公开(公告)号：US10588949B2

公开(公告)日：2020-03-17

申请号：US14776125

申请日：2014-03-14

Applicant: Bioverativ Therapeutics Inc.

Inventor： Mark Brader

IPC: A61K38/36 ,  A61K38/48 ,  A61K9/00 ,  A61K9/19 ,  A61K47/02 ,  A61K47/10 ,  A61K47/22 ,  A61K47/26 ,  A61M5/158 ,  A61M5/178 ,  A61M5/19

Abstract: The present invention provides formulations comprising a Factor IX-FcRn Binding Partner (FIXFBP) polypeptide, and methods of administering FIXFBP.

公开(公告)号：US11642398B2

公开(公告)日：2023-05-09

申请号：US16773634

申请日：2020-01-27

Applicant: BIOVERATIV THERAPEUTICS INC.

Inventor： Mark Brader

IPC: A61K38/36 ,  A61K38/48 ,  A61K9/00 ,  A61K9/19 ,  A61K47/02 ,  A61K47/10 ,  A61K47/22 ,  A61K47/26 ,  A61M5/158 ,  A61M5/178 ,  A61M5/19

CPC classification number: A61K38/4846 ,  A61K9/0019 ,  A61K9/19 ,  A61K47/02 ,  A61K47/10 ,  A61K47/22 ,  A61K47/26 ,  A61M5/158 ,  A61M5/178 ,  A61M5/19 ,  C12Y304/21022 ,  C07K2319/30

Abstract: The present invention provides formulations comprising a Factor IX-FcRn Binding Partner (FIXFBP) polypeptide, and methods of administering FIXFBP.