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Patent Agency Ranking
公开(公告)号：US20200330757A1
公开(公告)日：2020-10-22
申请号：US16850720
申请日：2020-04-16
Applicant: Boston Scientific Scimed, Inc.
Inventor： Brian L. Schmidt , Benjamin Keith Stein , Keith R. Maile , William J. Linder , Ron A. Balczewski , Sarah Melissa Gruba , Tucker James Nelson , Aleksandra Kharam
Abstract: Embodiments herein relate to a medical device for treating a cancerous tumor, including an electric field generating circuit configured to generate one or more electric fields at or near a site of the cancerous tumor and control circuitry in communication with the electric field generating circuit. The medical device includes one or more supply wires in electrical communication with the electric field generating circuit and one or more supply electrodes. The supply electrodes are configured to deliver an electric field at or near the site of the cancerous tumor. The medical device can include one or more sensing wires in electrical communication with the control circuitry and one or more sensing electrodes. The sensing electrodes can be configured to measure an impedance of the cancerous tumor at at least two different electric field strengths. Other embodiments are also included herein.
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2.发明申请公开(公告)号：US20250073462A1
公开(公告)日：2025-03-06
申请号：US18819328
申请日：2024-08-29
Applicant: Boston Scientific Scimed, Inc.
Inventor： Brian L. Schmidt , Devon N. Arnholt , Michael J. Lyden , Michael J. Kane , Tucker James Nelson
Abstract: Embodiments herein relate to implantable systems for cancer treatment and related methods. In an embodiment, an implantable system for cancer treatment is included having a therapy output circuit configured to generate an electrical current for a plurality of electric field therapy electrodes to create one or more electric fields and control circuitry that causes the therapy output circuit to generate the one or more electric fields at frequencies selected from a range of between 10 kHz to 1 MHz within a bodily tissue. The control circuitry can be configured to select between operating in a first mode or a second mode of generating the electrical current for the electric field therapy electrodes based on a minimum electrical field strength threshold, wherein the first mode includes modulating amplitude of the electrical current and the second mode includes duty cycling of the electrical current. Other embodiments are also included herein.
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公开(公告)号：US20250099751A1
公开(公告)日：2025-03-27
申请号：US18893371
申请日：2024-09-23
Applicant: Boston Scientific Scimed, Inc.
Inventor： Brian L. Schmidt , Devon N. Arnholt , Michael J. Lyden , Michael J. Kane , Tucker James Nelson
Abstract: Embodiments herein relate to implantable systems and methods for treatment of pancreatic cancer. In an embodiment, a method of treating pancreatic cancer is included, the method including inserting an electrical stimulation lead through the inferior vena cava, a hepatic vein, and into the portal vein via a transjugular intrahepatic portosystem shunt (TIPS). The method can further include inserting the electrical stimulation lead into at least one of the superior mesenteric vein and the splenic vein. The method can further include positioning electrodes on the lead within at least one of the superior mesenteric vein and the splenic vein and delivering one or more electric fields through the electrodes to a treatment zone including at least a portion of the pancreas. The electric fields can be at frequencies and a field strength effective to prevent and/or disrupt cellular mitosis in a cell.
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公开(公告)号：US20250058104A1
公开(公告)日：2025-02-20
申请号：US18799398
申请日：2024-08-09
Applicant: Boston Scientific Scimed, Inc.
Inventor： Brian L. Schmidt , Devon N. Arnholt , Michael J. Lyden , Michael J. Kane , Tucker James Nelson
Abstract: Embodiments herein relate to implantable systems for cancer treatment and related methods. In an embodiment, an implantable system for cancer treatment is included having a plurality of implantable stimulation leads, a plurality of electric field therapy electrodes, a therapy output circuit, and control circuitry. The therapy output circuit can generate an electrical current for the plurality of electric field therapy electrodes to create one or more electric fields that are effective to prevent and/or disrupt cellular mitosis in a cell. The control circuitry can be configured to cause the electrical current to be distributed asymmetrically between working electrodes and counter electrodes amongst the plurality of electric field therapy electrodes. At least some of the plurality of electric field therapy electrodes are disposed on the plurality of implantable stimulation leads and in electrical communication with the therapy output circuit. Other embodiments are also included herein.
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公开(公告)号：US11420049B2
公开(公告)日：2022-08-23
申请号：US16850720
申请日：2020-04-16
Applicant: Boston Scientific Scimed, Inc.
Inventor： Brian L. Schmidt , Benjamin Keith Stein , Keith R. Maile , William J. Linder , Ron A. Balczewski , Sarah Melissa Gruba , Tucker James Nelson , Aleksandra Kharam
Abstract: Embodiments herein relate to a medical device for treating a cancerous tumor, including an electric field generating circuit configured to generate one or more electric fields at or near a site of the cancerous tumor and control circuitry in communication with the electric field generating circuit. The medical device includes one or more supply wires in electrical communication with the electric field generating circuit and one or more supply electrodes. The supply electrodes are configured to deliver an electric field at or near the site of the cancerous tumor. The medical device can include one or more sensing wires in electrical communication with the control circuitry and one or more sensing electrodes. The sensing electrodes can be configured to measure an impedance of the cancerous tumor at at least two different electric field strengths. Other embodiments are also included herein.
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