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1.发明授权Compound marked with tritium, its preparation and its use in the location of nuclear receptors of retinoids 失效化合物标记的三氯乙烯，其制备及其在核酸受体的位置使用
公开(公告)号：US5073361A
公开(公告)日：1991-12-17
申请号：US553812
申请日：1990-07-19
申请人： Braham Shroot , Michel Darmon
发明人： Braham Shroot , Michel Darmon
CPC分类号： G01N33/534 , A61K51/0402 , C07C65/26 , A61K2123/00
摘要： 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid marked with tritium; its preparation; and its use as a radioactive marker, in the titration of nuclear receptors of retinoids in the presence of contaminating CRABP, or in the measurement of the affinity of retinoids for these nuclear receptors.
摘要翻译： 用氚标记的6- [3-（1-金刚烷基）-4-甲氧基苯基] -2-萘甲酸; 其准备; 以及其作为放射性标记物的用途，在存在污染性CRABP时滴定类视黄醇的核受体，或用于测定类视黄醇对这些核受体的亲和力。
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2.发明授权Compound marked with tritium, its preparation and its use in the location of nuclear receptors of retinoids 失效化合物标有氚，其制备及其在类维生素A的核受体位置的应用
公开(公告)号：US5149631A
公开(公告)日：1992-09-22
申请号：US675804
申请日：1991-03-27
申请人： Braham Shroot , Michel Darmon
发明人： Braham Shroot , Michel Darmon
IPC分类号： A61K51/04 , C07C65/26 , G01N33/534
CPC分类号： G01N33/534 , A61K51/0402 , C07C65/26 , A61K2123/00
摘要： 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid marked with tritium; its preparation; and its use as a radioactive marker, in the titration of nuclear receptors of retinoids in the presence of contaminating CRABP, or in the measurement of the affinity of retinoids for these nuclear receptors.
摘要翻译： 用氚标记的6- [3-（1-金刚烷基）-4-甲氧基苯基] -2-萘甲酸; 其准备; 以及其作为放射性标记物的用途，在存在污染性CRABP时滴定类视黄醇的核受体，或用于测定类视黄醇对这些核受体的亲和力。
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公开(公告)号：US4721006A
公开(公告)日：1988-01-26
申请号：US722983
申请日：1985-04-15
申请人： Michel Darmon
发明人： Michel Darmon
CPC分类号： B25J9/106 , F16H21/04 , F16H21/44 , Y10T74/18928 , Y10T74/20582 , Y10T74/20594
摘要： The mechanism comprises a movable member having three axes converging in a center of the mechanism, i.e. two main axes guided each by a crank, and a driven axis on which any point follows a substantially circular path centered in the above center. This is due to an appropriate geometry. A driven member may be linked to the movable part about the driven axis, and to a parallelism rod which is in turn linked to one of the cranks. The driven member remains then parallel to itself when the mechanism is actuated, that is, when the one crank is rotated with respect to a carrier member. The driven member may be a cylindrical side window of a car.
摘要翻译： 该机构包括具有会聚在机构的中心的三个轴的可动构件，即每个由曲柄引导的两个主轴，以及从动轴，其中任何点都围绕以上述中心为中心的大致圆形路径。 这是由于适当的几何形状。 被驱动构件可以围绕从动轴线连接到可动部分，并且可以连接到平行杆，该平行杆又连接到曲柄中的一个。 当机构被致动时，即当一个曲柄相对于承载构件旋转时，被驱动构件保持与其自身平行。 从动构件可以是汽车的圆柱形侧窗。
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公开(公告)号：US4718292A
公开(公告)日：1988-01-12
申请号：US722982
申请日：1985-04-15
申请人： Michel Darmon
发明人： Michel Darmon
CPC分类号： B25J9/106 , F16H21/04 , F16H21/44 , Y10T74/18928 , Y10T74/20582 , Y10T74/20594
摘要： The mechanism comprises a movable part having one main point actuated by a crank, another main point guided along a slide having a desired profile, and a driven point which follows a desired path, depending upon the path of the two main points. A driven member is articulated to the movable member about the driven point. Moreover, the driven member is guided with respect to the crank along a path which is in a certain similarity with respect to the path of said other main point. The driven member moves parallel to itself when the crank is actuated.
摘要翻译： 该机构包括可移动部分，其具有由曲柄致动的一个主要点，沿着具有期望轮廓的滑块引导的另一个主要点，以及依赖于所需路径的驱动点，这取决于两个主要点的路径。 被驱动构件围绕驱动点铰接到可移动构件。 此外，被驱动构件相对于曲柄沿着相对于所述另一个主要路径的路径具有一定相似性的路径被引导。 当曲柄致动时，从动构件平行于自身移动。
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