公开(公告)号：US20120239123A1

公开(公告)日：2012-09-20

申请号：US13358337

申请日：2012-01-25

申请人： Bryan Weber ,  Joseph Coakley ,  John Potosky

发明人： Bryan Weber ,  Joseph Coakley ,  John Potosky

IPC分类号： A61F7/10

CPC分类号： A61F7/10 ,  A61B2090/0463 ,  A61F7/02 ,  A61F2007/0056 ,  A61F2007/0075 ,  A61F2007/0095 ,  A61F2007/029

摘要： Application systems, disposable interface assemblies and methods for cooling subcutaneous lipid-rich tissue. One embodiment of an application system includes a cooling unit, a cryoprotectant vessel, a contact member and an array of selectively addressable heating elements. The cryoprotectant vessel is configured to contain a fluidic cryoprotectant such that at least a portion of the cryoprotectant is cooled by the cooling unit to a desired base temperature. The contact member is attached to the cryoprotectant vessel and includes a backside in contact with the cryoprotectant and a front side opposite the backside. The contact member is configured to allow the cryoprotectant to flow from the backside to the front side. The array of selectively addressable heating elements is carried by the contact member.

摘要翻译： 应用系统，一次性界面组件和用于冷却皮下脂质富集组织的方法。 应用系统的一个实施例包括冷却单元，冷冻保护容器，接触构件和选择性寻址加热元件的阵列。 冷冻保护剂容器被配置为容纳流体冷冻保护剂，使得至少一部分冷冻保护剂被冷却单元冷却至所需的基础温度。 接触构件附接到冷冻保护剂容器，并且包括与冷冻保护剂接触的背面和与背面相对的前侧。 接触构件被配置为允许冷冻保护剂从背侧流动到前侧。 选择性寻址的加热元件的阵列由接触构件承载。

公开(公告)号：US10722395B2

公开(公告)日：2020-07-28

申请号：US13358337

申请日：2012-01-25

申请人： Bryan Weber ,  Joseph Coakley ,  John Potosky

发明人： Bryan Weber ,  Joseph Coakley ,  John Potosky

IPC分类号： A61F7/00 ,  A61F7/10 ,  A61F7/02 ,  A61B90/00

摘要： Application systems, disposable interface assemblies and methods for cooling subcutaneous lipid-rich tissue. One embodiment of an application system includes a cooling unit, a cryoprotectant vessel, a contact member and an array of selectively addressable heating elements. The cryoprotectant vessel is configured to contain a fluidic cryoprotectant such that at least a portion of the cryoprotectant is cooled by the cooling unit to a desired base temperature. The contact member is attached to the cryoprotectant vessel and includes a backside in contact with the cryoprotectant and a front side opposite the backside. The contact member is configured to allow the cryoprotectant to flow from the backside to the front side. The array of selectively addressable heating elements is carried by the contact member.

公开(公告)号：US20110300079A1

公开(公告)日：2011-12-08

申请号：US13011640

申请日：2011-01-21

申请人： Paul W. Martens ,  John Potosky

发明人： Paul W. Martens ,  John Potosky

IPC分类号： A61K31/08 ,  A61P39/00 ,  A61K31/79 ,  A61K31/19 ,  A61K31/047 ,  A61K31/10

CPC分类号： A61F7/10

摘要： A composition or cryoprotectant for use with a system for improved cooling of subcutaneous lipid-rich tissue of a subject having skin is provided. The cryoprotectant is a non-freezing liquid, gel, or paste for allowing pre-cooling of a treatment device below about 0° C. while preventing the formation of ice thereon. The cryoprotectant may also prevent freezing of the treatment device to the skin and protect tissue of a subject from freezing damage due to, e.g., ice formation. The cryoprotectant can also include an authentication or anti-counterfeiting agent to authenticate an origin of the cryoprotectant, a lubricating agent to increase lubriciousness of the cryoprotectant, and a thixotropic or pseudoplastic agent in an amount effective substantially to render the gel dimensionally stable unless agitated.

摘要翻译： 提供了用于与具有皮肤的受试者的皮下富含脂质组织的改善冷却的系统一起使用的组合物或冷冻保护剂。 冷冻保护剂是一种非冻结液体，凝胶或糊剂，用于使治疗装置预冷至低于约0℃，同时防止其上形成冰​​。 冷冻保护剂还可以防止治疗装置冻结到皮肤并且保护受试者的组织免受例如冰层形成的损伤。 冷冻保护剂还可以包括用于认证冷冻保护剂的来源的认证或防伪剂，增加冷冻保护剂的润滑性的润滑剂，以及触变性或假性试剂，其量基本上使凝胶尺寸稳定，除非被搅拌。