公开(公告)号：US11530242B2

公开(公告)日：2022-12-20

申请号：US17259400

申请日：2019-07-16

Applicant: UNM RAINFOREST INNOVATIONS ,  Bryce Chackerian ,  Oliver Rixe

Inventor： Bryce Chackerian ,  Oliver Rixe

IPC: A61K39/00 ,  A61K39/12 ,  C12N7/00 ,  C12N15/62 ,  A61K38/00 ,  C07K7/08 ,  A61K45/06

Abstract: An immunogen includes an antigenic EGFRvIII peptide linked to a Qβ bacteriophage virus-like particle (VLP) carrier. The antigenic EGFRvIII peptide has at least 53%, at least 61%, at least 69%, at least 76%, at least 84%, or at least 92% sequence similarity amino acid similarity to LEEKKGNYVVTDH (SEQ ID NO:1).

公开(公告)号：US20210253641A1

公开(公告)日：2021-08-19

申请号：US17259400

申请日：2019-07-16

Applicant: Bryce Chackerian ,  Oliver Rixe ,  UNM RAINFOREST INNOVATIONS

Inventor： Bryce Chackerian ,  Oliver Rixe

IPC: C07K7/08 ,  A61K45/06 ,  C12N7/00 ,  A61K39/00

Abstract: An immunogen includes an antigenic EGFRvIII peptide linked to a Qβ bacteriophage virus-like particle (VLP) carrier. The antigenic EGFRvIII peptide has at least 53%, at least 61%, at least 69%, at least 76%, at least 84%, or at least 92% sequence similarity amino acid similarity to LEEKKGNYVVTDH (SEQ ID NO:1).