公开(公告)号：US20250057545A1

公开(公告)日：2025-02-20

申请号：US18718713

申请日：2022-12-13

Applicant: UNM Rainforest Innovations

Inventor： Nathan MORRELL ,  Dimitri MADDEN ,  Lauren A. OSTERMANN ,  Diego Enrique RODRIGUEZ ,  August William FINKE ,  Ethan C. DARWIN

IPC: A61B17/16 ,  A61F2/30 ,  A61F2/42

Abstract: A procedure and device that resolves CMC arthritis by mimicking a thumb CMC joint fusion, while avoiding common shortcomings of the fusion surgery as well as existing alternative surgeries for thumb CMC arthritis which can also replace the trapezium bone in the carpometacarpal joint with a stemmed trapezial implant. In addition, the trapezial implant device replicates skeletal anatomy and is configured to directly contact native bone and cartilage in order to more evenly distribute stresses.

公开(公告)号：US20250043285A1

公开(公告)日：2025-02-06

申请号：US18761527

申请日：2024-07-02

Applicant: UNM Rainforest Innovations

Inventor： Vojo Deretic ,  Graham Timmins ,  Rujeena Javed

IPC: C12N15/113 ,  A61K31/357 ,  A61K31/7034 ,  A61K38/10 ,  A61K45/06 ,  A61P3/00

Abstract: The present invention relates to discovery that modulators of ATG8 and/or ATG9A act in sequence to orchestrate the sealing of autophagosomal membranes. The present invention is directed to use of these agents and this mechanism in the treatment of various disease states and/or conditions, especially cancer.

公开(公告)号：US12208164B2

公开(公告)日：2025-01-28

申请号：US17434363

申请日：2020-02-27

Applicant: UNM Rainforest Innovations

Inventor： C. Jeffrey Brinker ,  Jimin Guo ,  Wei Zhu

IPC: A61K9/107 ,  A61K31/704 ,  A61K33/242 ,  A61K47/10 ,  A61K47/24 ,  A61K47/68 ,  A61K47/69 ,  A61P35/00

Abstract: A method to prepare a population of metal-organic polyhedra (MOP) supported micelle nanoparticles (NPs), and a composition comprising MOP supported micelle NPs, are provided.

公开(公告)号：US12204249B1

公开(公告)日：2025-01-21

申请号：US17853630

申请日：2022-06-29

Applicant: UNM RAINFOREST INNOVATIONS

Inventor： Steven R. J. Brueck ,  Alexander Neumann ,  Vineeth Sasidharan

IPC: G03F7/00 ,  G02B7/00 ,  G02B27/09 ,  G02B27/10

Abstract: A system for oblique incidence nanopatterning a sample using a grating beam-splitter is disclosed. The system also includes a grating beam-splitter on a tip-tilt adjustable mount. The system also includes a photoresist coated sample mounted on a tip-tilt-z adjustable mount. The system also includes an alignment system to allow adjustment of the tip-tilt adjustable mounts so that a surface of the grating beam-splitter and a surface of the photoresist coated sample are substantially parallel. The system also includes a laser operating at a wavelength suitable for exposure of the photoresist. The system also includes an optical system to deliver a laser beam at oblique incidence to the grating beam-splitter to expose the photoresist coated sample. The system also includes means to control an exposure dose of the laser beam. A system using two grating beam-splitters to provide increased alignment tolerance is also disclosed.

公开(公告)号：US20240377246A1

公开(公告)日：2024-11-14

申请号：US18554594

申请日：2022-01-26

Applicant: UNM RAINFOREST INNOVATIONS

Inventor： Steven R. J. BRUECK ,  Alexander NEUMANN ,  Payman ZARKESH-HA

IPC: G01J1/06 ,  G01J1/44 ,  G01J3/02 ,  G01J3/18 ,  G01J3/28 ,  G02B6/12 ,  G02B6/122 ,  G02B6/124 ,  H01L27/144 ,  H01L31/02 ,  H01L31/0216 ,  H01L31/0232 ,  H01L31/103

Abstract: An occupancy sensor covering a wide field in an integrated chip is disclosed. The occupancy sensor includes an array of grating coupled waveguide sensors wherein continuous wave (cw) signals monitor an ambient light field for dynamic changes on times scales of seconds, and high frequency signals map in three-dimensions of the space using time-of-flight (TOF) measurements, pixel level electronics that perform signal processing; array level electronics that perform additional signal processing; and communications and site level electronics that interface with actuators to respond to occupancy sensing.

公开(公告)号：US20240316174A1

公开(公告)日：2024-09-26

申请号：US18269796

申请日：2022-01-27

Applicant: UNM RAINFOREST INNOVATIONS

Inventor： KATHRYN MARIE FRIETZE ,  NICOLE WARNER

IPC: A61K39/12 ,  A61K47/64 ,  A61P31/14 ,  C07K14/005 ,  C12N7/00

CPC classification number: A61K39/12 ,  A61K47/64 ,  A61P31/14 ,  C07K14/005 ,  C12N7/00 ,  C12N2770/24022 ,  C12N2770/24023 ,  C12N2770/24033 ,  C12N2795/18122 ,  C12N2795/18123

Abstract: The present invention is directed to virus-like particles (VLPs) which display immunogenic peptides of Flavivirus non-structural Protein 1 (NS1) derived from Dengue Virus (DENY), immunogenic compositions and vaccines against Flavivirus infection and related methods of immunizing and/or vaccinating subjects against Flavivirus, especially Dengue infections. The VLPs according to the present invention comprise polypeptide subunits of Dengue NS 1 protein which has been conjugated to the surface of a VLP as described herein, often a VLP derived from a Qbeta (Pβ) or AP205 bacteriophage.

公开(公告)号：US20240313533A1

公开(公告)日：2024-09-19

申请号：US18225087

申请日：2023-07-21

Applicant: UNM Rainforest Innovations

Inventor： Ali Bidram ,  Matthew Reno ,  Binod Poudel ,  Adam Summers

IPC: H02J3/04 ,  G06N20/00 ,  H01H71/74

CPC classification number: H02J3/04 ,  G06N20/00 ,  H01H71/74

Abstract: A system, device and method that provides for the addition of Local Adaptive Modular Protection (LAMP) units to the protection system to guarantee its reliable operation under extreme events when the operation of the APS is compromised.

公开(公告)号：US20240297324A1

公开(公告)日：2024-09-05

申请号：US18655565

申请日：2024-05-06

Applicant: UNM RAINFOREST INNOVATIONS

Inventor： Shuya WEI ,  Cameron CARUGATI ,  Christopher FETROW

IPC: H01M8/18

CPC classification number: H01M8/188

Abstract: Rechargeable electrochemical devices and methods for the same are disclosed. The electrochemical devices may include an anode, a cathode, and an electrolyte disposed between the anode and the cathode. The electrolyte may include a deep eutectic mixture and an electrolyte additive. The deep eutectic mixture may include an ion coordinated complex prepared from a combination of aluminum chloride (AlCl3) and an amide or a combination of AlCl3 and an organic salt.

公开(公告)号：US20240291003A1

公开(公告)日：2024-08-29

申请号：US18585788

申请日：2024-02-23

Applicant: UNM RAINFOREST INNOVATIONS ,  U.S. GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE

Inventor： John Bryan PLUMLEY ,  Lok-kun TSUI ,  Thomas Liang-Shi PENG ,  Fernando GARZON

IPC: H01M8/04082 ,  F23R3/28 ,  H01M4/90 ,  H01M8/00 ,  H01M8/04014 ,  H01M8/12 ,  H01M8/1253 ,  H01M8/2425

CPC classification number: H01M8/04201 ,  F23R3/28 ,  H01M4/9033 ,  H01M8/004 ,  H01M8/04022 ,  H01M8/1253 ,  H01M8/2425 ,  H01M2008/1293

Abstract: An integrated fuel cell and combustion system that integrate both a fuel cell and a combustion system, such that the fuel cell and the combustion system share a a fuel source and an oxidizer source, and the fuel cell and combustion system can be utilized singularly or simultaneously based on the needs for power generation.

公开(公告)号：US12074228B2

公开(公告)日：2024-08-27

申请号：US17850045

申请日：2022-06-27

Applicant: UNM RAINFOREST INNOVATIONS

Inventor： Sang M. Han ,  Omar Abudayyeh ,  David Wilt ,  Nathan Gapp

IPC: H01L31/02 ,  B82Y40/00 ,  C01B32/158 ,  H01L31/0224 ,  H01L31/05 ,  H01L31/073 ,  H02S40/44 ,  H10K30/82 ,  B82Y30/00

CPC classification number: H01L31/02008 ,  B82Y40/00 ,  C01B32/158 ,  H01L31/0201 ,  H01L31/022425 ,  H01L31/05 ,  H01L31/073 ,  H02S40/44 ,  H10K30/821 ,  B82Y30/00 ,  Y10S977/75 ,  Y10S977/752 ,  Y10S977/842 ,  Y10S977/89 ,  Y10S977/891 ,  Y10S977/901 ,  Y10S977/948

Abstract: A solar cell structure is disclosed that includes a first metal layer, formed over predefined portions of a sun-exposed major surface of a semiconductor structure, that form electrical gridlines of the solar cell; a network of carbon nanotubes formed over the first metal layer; and a second metal layer formed onto the network of carbon nanotubes, wherein the second metal layer infiltrates the network of carbon nanotubes to connect with the first metal layer to form a first metal matrix composite comprising a metal matrix and a carbon nanotube reinforcement, wherein the second metal layer is an electrically conductive layer in which the carbon nanotube reinforcement is embedded in and bonded to the metal matrix, and the first metal matrix composite provides enhanced mechanical support as well as enhanced or equal electrical conductivity for the electrical contacts against applied mechanical stressors to the electrical contacts.