公开(公告)号：US11959856B2

公开(公告)日：2024-04-16

申请号：US15701014

申请日：2017-09-11

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Imran R. Malik ,  Xiomara Linnette Madero ,  Erika F. Garcia ,  Sheel Mukesh Shah ,  Axel Scherer

IPC: G01N21/64 ,  C12Q1/6851

CPC classification number: G01N21/6486 ,  C12Q1/6851 ,  C12Q1/6851 ,  C12Q2537/143 ,  C12Q2537/165 ,  C12Q2565/629

Abstract: Methods and algorithms for a multiplexed single detection channel amplification process and quantification of generated amplicons is presented. Various mathematical approaches for quantifying and verifying the amplicons in a reaction are presented. Usage of such methods and approaches allow upgrading of existing single and multiple channel instruments for further multiplexing capabilities.

公开(公告)号：US09791372B2

公开(公告)日：2017-10-17

申请号：US13958479

申请日：2013-08-02

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Imran R. Malik ,  Xiomara Linnette Madero ,  Erika F. Garcia ,  Sheel Mukesh Shah ,  Axel Scherer

IPC: G01N21/64 ,  C12Q1/68

CPC classification number: G01N21/6486 ,  C12Q1/6851 ,  C12Q2537/143 ,  C12Q2537/165 ,  C12Q2565/629

Abstract: Methods and algorithms for a multiplexed single detection channel amplification process and quantification of generated amplicons is presented. Various mathematical approaches for quantifying and verifying the amplicons in a reaction are presented. Usage of such methods and approaches allow upgrading of existing single and multiple channel instruments for further multiplexing capabilities.