公开(公告)号：US20250027165A1

公开(公告)日：2025-01-23

申请号：US18714695

申请日：2022-12-02

Applicant: CAMBRIDGE ENTERPRISE LIMITED

Inventor： Richard GILBERTSON ,  Eric RAHRMANN ,  David SHORTHOUSE

IPC: C12Q1/6886 ,  G01N33/574 ,  G16B5/00 ,  G16H50/30

Abstract: A method for the detection or prognosis of cancer and/or metastasis is provided. Tumour samples may be used to determine the presence of a mutation within the sodium leak channel (NALCN). A risk score of cancer and/or metastasis can be determined based on if the mutation causes a reduction in the pore size of NALCN. A computational model, a composition, and a kit are also provided.